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dexadrine / d-amphetamine


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My brand new shrink just prescribed d-amphetamine for MDD/recurrent/refractory. I'll be taking it on top of Abilify 15 mg and Effexor 450 mg (plus a buttload of antihypertensives thanks to Effexor). (In the name of changing only one thing at a time, we're not touching the Abilify or Effexor for the time being. More about that on a different forum.)

Was just wondering if anyone out there has tried d-amphetamine (yep, generics -- only the best for me!). What has your experience been? From Jerod's writeup on it, I think it may not be too bad in terms of getting my energy up and maybe even losing weight (yay!). But I just wondered if there was a firsthand account someone would be willing to share.

Thanks,

clumsycrawling

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It's my favorite of the CNS stims.  It's stronger than the methyphenidates and I found it to have fewer side effects than Adderal.

The sustained release spansules are preferable as there tends to be a bit of a "crash" when the standard release variant wears off.

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The sustained release spansules are preferable as there tends to be a bit of a "crash" when the standard release variant wears off.

The script did say spansules, but the label on what i got doesn't -- but it has "SA" after the drug name. Hopefully this means something like "sustained action"?

Also, how long after I take it will I start to feel the effect -- minutes? hours?

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OMIGOD!!! This stuff is great! I want more and more and more! Yippee!!! I wasn't tired dragging my class up and down three flights three times this morning, I wasn't dragging on my way back up to my classroom after they left, and I swept through my room for a final cleanup like a tornado in reverse. POW! POW! POW! Yeeeeee-haw!

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The other shoe:

You'll get some tolerance after a while so the euphoric effect won't be as great.  You'll want to take a reduced dose or not take it at all for a few days every now and then to keep your tolerance from getting too high. 

Don't talk like you did in this post in front of your pdoc, ie, "I want more and more and more" as they might be tempted to take it away from you. 

It's some strong shit so make sure you treat it with respect.

It does make you feel pretty damn good for the first few hours though.

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Thanks for the caution, VE. I have a fairly healthy fear of addiction, and I've been managing hydrocodone okay for the past six months, so hopefully I'll be able to extend the same commonsensical fear to amphetamine. No, I'd never let loose the way I did in my post.  ;)

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  • 3 weeks later...

My brand new shrink just prescribed d-amphetamine for MDD/recurrent/refractory. I'll be taking it on top of Abilify 15 mg and Effexor 450 mg (plus a buttload of antihypertensives thanks to Effexor). (In the name of changing only one thing at a time, we're not touching the Abilify or Effexor for the time being. More about that on a different forum.)

Was just wondering if anyone out there has tried d-amphetamine (yep, generics -- only the best for me!). What has your experience been? From Jerod's writeup on it, I think it may not be too bad in terms of getting my energy up and maybe even losing weight (yay!). But I just wondered if there was a firsthand account someone would be willing to share.

Thanks,

clumsycrawling

<{POST_SNAPBACK}>

I tried Dexadrine and really HATED it. The first dose sent me down the depressive tunnel faster than the speed of light. I found Adderall to be a much kinder med.

darkdreams

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  • 4 weeks later...

Dextroamphetamine is the second strongest stimulant after Desoxyn (Methamphetamine Hcl) Take it easy, I wonder what dose you are taking? I take Ritalin IR and find it pretty strong in the mental effects, sometimes i ahve sleep troubles,

Take it easy

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Yep 5mg day is low alright, I was scripted 80mgs Ritalin=40mg Dexedrine according to the tables. I wonder if you will even feel 5mgs considering the other meds you are taking.

Dexedrine doses are indicated at up to 60mg for ADD/HD 100mg for Narcolepsy. so i wonder how 5mgs effects you.

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It's my favorite of the CNS stims.  It's stronger than the methyphenidates and I found it to have fewer side effects than Adderal.

The sustained release spansules are preferable as there tends to be a bit of a "crash" when the standard release variant wears off.

<{POST_SNAPBACK}>

What are brand and full generic names and is it available in the U.S.? I just don't think Adderall is cutting it for me, anymore. I've been pretty stable on all my other meds for a few months, so I want to push the pdoc on trying something new for the ADD (he understandably doesn't like to mess with more than one or two meds at a time).

Adderall's the only CNS stimulant I've taken (other than Provigil). Depression is definitely under control, but I still seem to severely lack the motivation and energy I used to have. I've been on Adderall for 6-7 years without more than a day or two break and without a dosage change (except when I switched to XR a couple of years ago). For the last few weeks, I've seriously been thinking about popping two of those capsules in the morning, but I'm worried that it would be too much and my pdoc is out until after Labor Day. I wish I had some lower dose immediate release to supplement.

What do you think? Try a higher dose first (w/pdoc's consent, of course), or is it time to give something else a whirl?

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Always ask your Doc about changes, but if you are falling in your treatment its time to reasess. I don't know if you have tried Dexedrine-Adderall is 75%Dex, but many report it being smoother.

If you have been on Amphetamines for 7 years you are obviously tolerant to them. Desoxyn (Methamphetamine Hcl) is the step above and is indicated for folks who are tolerant to Amphetamines. Many who have tried it have reported that it produces improved results with greater mental benefits with little somatic effects, it is only available in 5mg IR tabs so perhaps thas an option, or an increase of adderall, i wonder what dose of Adderall you are taking.

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It's almost impossible to get an rx for Desoxyn right now as it's pharmaceutical crystal meth. 

Dexedrine is dextroamphetimine sulfate and is available in in 5, 10, and 15 mg SR spansules and 5 and 10 mg short acting pills. (I think)

Both are available as a generic from a variety of manufacturers.

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Desoxyn is not crystal Meth. thay is a street drug. Desoxyn is a medical medication which is the best med for many with sever ADD/hd narcolepsy. I know of some who have used it for many many years with no problems. Granted it is reserved for refractory patients, but for  them has been the difference between a functional like or disability-get it straight.

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Desoxyn is not crystal Meth. thay is a street drug. Desoxyn is a medical medication which is the best med for many with sever ADD/hd narcolepsy. I know of some who have used it for many many years with no problems. Granted it is reserved for refractory patients, but for  them has been the difference between a functional like or disability-get it straight.

<{POST_SNAPBACK}>

Desoxyn Online, Description, Chemistry, Ingredients ...

DESOXYN (methamphetamine hydrochloride tablets, USP), chemically known as (S)-N, ... For information on ordering Desoxyn Online, please click the "online ...

www.rxlist.com/cgi/generic2/methamphetamine.htm - 20k - Cached - Similar pages

That was at the very top of the first page of this Google search.

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"A rose by any other name...."

You are all correct. Desoxyn is methamphetamine hydrochloride, "crystal meth" is a street drug that may contain methamphetamine HCl as well as other closely related chemicals and other adulterants.

  From Erowid.org:

Overview

Methamphetamine (also known as speed, meth, crystal, crank, tina, and sometimes confusingly called ice) is a chemical widely known for its stimulant properties on the human body. It is frequently confused with other drugs that share similar effects, including amphetamine, 4-methyl-aminorex, ephedrine, caffeine, and other chemicals, both legal and illegal.

Terminology

In this document, we shall refer to the drugs by their common chemical names, rather than by "street names", since the street names do not have a one-to-one correspondence to actual chemicals. For example, the term "speed" can mean methamphetamine or amphetamine. The term "ice" is generally considered to apply to 4-methyl-aminorex, but is often used to refer to relatively pure (and in some cases, not so pure) forms of methamphetamine.

We shall use the term "methamphetamine" to refer to the substance in either its free base (i.e. simple, unadorned) or salt (usually hydrochloride) form. When precision is needed, we shall explicitly state one form or the other.

Key points:  Desoxyn contains methamphetamine HCl which is a highly addictive and easily abused stimulant, which should be used with care under a doctor's supervision.

A.M.

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I know people who have used Desoxyn for several decades, to treat Narcolepsy (which it seems to be one of the most effective meds) one chap i know of, has taken it for over 40 years at 70-80mgs daily 4-5 15mg SR, in the morning left him like a normal person all day, now 4-5mg Ir 4x daily with less effective results-thanks to the more effective Abott version becoming discontinued, to remain functional. It is only addictive it the individual allows themself to become so.

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I've been seeing the same pdoc, an ADD specialist, for over 5 years and have tried every stimulant on the market other than desoxyn.  He said that he'd get investigated if he prescribed it and he knows of no pharmacy in the area (Nashville) which carries it.  Things might be different elsewhere, but there has been a "meth epidemic" around here that is being majorly played up by the media.  While my pdoc agreed that if anyone might benefit from giving desoxyn a try it's me, he flat out could not prescribe it without having both him and me investigated. 

It's probably a regional thing, but politics around here make it impossible to get.

I've already had one ADD specialist pdoc driven into bankruptcy by having to defend himself against charges of over-prescribing stimulants and everyone else is cautious of keeping the same thing from happening to them.

Desoxyn PI sheet attached:

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Do you have a couple of days when you can be a bit non productive in order to take a med holiday? Have you tried that already? I may try this one of these days but I don't like the idea of being scattered.

snipt think Adderall is cutting it for me, anymore. I've been pretty stable on all my other meds for a few months, so I want to push the pdoc on trying something new for the ADD (he understandably doesn't like to mess with more than one or two meds at a time).

Adderall's the only CNS stimulant I've taken (other than Provigil). Depression is definitely under control, but I still seem to severely lack the motivation and energy I used to have. I've been on Adderall for 6-7 years without more than a day or two break and without a dosage change (except when I switched to XR a couple of years ago). For the last few weeks, I've seriously been thinking about popping two of those capsules in the morning, but I'm worried that it would be too much and my pdoc is out until after Labor Day. I wish I had some lower dose immediate release to supplement.

What do you think? Try a higher dose first (w/pdoc's consent, of course), or is it time to give something else a whirl?

<{POST_SNAPBACK}>

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