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NYT: Eli Lili Plays Down Zyprexa Health Risks (shock shock)


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The article is tinged with the usual NYT FUD but better than average.

http://www.nytimes.com/2006/12/17/business...&ei=5087%0A

The drug maker Eli Lilly has engaged in a decade-long effort to play down the health risks of Zyprexa, its best-selling medication for schizophrenia, according to hundreds of internal Lilly documents and e-mail messages among top company managers.

...

Lilly

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zyprexa was such good stuff for me, but after horrific weight gain and increased blood sugar right away after starting it, i had to switch to risperdal.

it isn't surprising at all, yet is very sad that pharm companies have to edge around the truth and in cases outright lie about their products.

i know someone who developed diabetes from zyprexa. i'm happy i quit taking it, because i would have developed diabetes too.

maybe they ought to think of the health of the people taking the drug rather than the profits, oh wait, that's not what they do...

i'm sure zyperxa would continue to be a big seller. zyperxa in short-term doses can calm mania like nothing else, and is very useful in the hospital. also, it doesn't have killer side effects for everyone, so some people could maintain on it.

lilly is just short-sighted. no surprise there.

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That is exactly why being a member of a community like this is a proactive step in managing our illnesses.

I bet there isn't a person here who isn't already aware of the fact that Zyprexa is the biggest offender when it comes to weight gain.

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I bet there isn't a person here who isn't already aware of the fact that Zyprexa is the biggest offender when it comes to weight gain.

I though the AAPs were all much of a muchness in terms of weight gain.

It took over a year of seroquel to gain as much as I did in a couple months of zyprexa. This is pretty much settled. There has been a multimillion dollar class action suit and everything. I'm amazed that it's still being used long term.

It seems that clozerlil is hardly ever used due to the agranulocytosis (white blood cell depletion) risk, but that can be detected early with simple blood tests. The risks posed by zyprexa are much more pernicious.

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I have a book called 'Psychiatric Drugs Explained' which says that Lilly never published the trial reports of Zyprexa because the suicide rate was extremely high. I am convinced that no matter how much I love it, it's not a good thing to be on long term and I will ditch it as soon as I speak to my p-doc on Friday. Does clozaril have a high weight gain profile?

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There is a huge suicide risk associated with SZ as well IIRC. There is no way for a study determine if an individual is more likely to attempt suicide on or off a medication. It is possible for fear mongers who don't understand how to intemperate data to use this to further their own agenda. Take all claims regarding medications causing suicide attempts with a huge grain of salt.

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Blackbird: If the zyprexa induced weight gain is compounding your ED issues, clozaril would definitely be one to look into. Anything would be better. People gain 100 pounds on the stuff and diet has nothing to do with it. Sometimes there is nothing you can do by way of diet or working out to prevent it.

I had an odd feeling that I was overweight and malnourished at the same time.

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A doctor friend of mine, while blogging about this article, said that Eli Lilly is also a major manufacturer of diabetes drugs.

Zyprexa has been a wonder drug for a lot of people, and I don't want to blackball it for its side effects. But damn sure does Eli Lilly have a responsibility to disclose what those are.

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  • 3 weeks later...

When I was at the pdoc yesterday the Eli Lilly rep came in. He acted as if he owned the place, just walked in the Employees Only door and was rummaging back in the office. He then came out and refilled the Cymbalta and Zyprexa brochures. He looked like he was a mafioso with his slicked back hair, pinned striped suit and obviously insanely expensive watch. After my recent and continuing bout with Cymbalta withdrawal I was ready to smack him. Pharma reps are worse than used car salesmen. I think he should take me out to a nice dinner instead of the doctor - I've paid enough to Eli Lilly both in dollars and general suffering.

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I love zyprexa but just can't use it except in emergency the weight gain and akathesia(sp?) does me in. You'd think by now they'd have figured out what causes the "eat everything in the refrigerator, constant movement, and massive weight gain." I swear big pharma is the way to go-anyone got money to invest?jeez...

lilie

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Well from what I have read under the current administration the pharmaceutical companies have virtually been running the FDA. I'm all for medications - they are necessary - but corporations are all about making money. I do not doubt for a minute that they would cover this stuff up to ensure they make a larger profit. My pdoc talked about Zyprexa and Seroquel once to me - he said if I continue going "nutso" he would think about putting me on them. I told him there is no way, all these psychotropic drugs (except Wellbutrin) make me gain weight. If I took Seroquel or Zyprexa I would gain 20lbs as soon as the pill hit my tongue. Before taking all these drugs a year and a half ago I was 160, now I'm 225!

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