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OK, i have been on Depakote ER now for almost two months. I am still tired all the time. I don't know how long I should give this to clear up before asking to go back on non ER Depakote. The fatigue could be seasonally based ... but it definitely began when i started taking the ER. I don't think that's a coincidence.

Anyone else have experience with this who could give me an idea how long the fatigue took to clear? I hate running around changing meds w/o need, but this fatigue is kicking my ass.

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I'd give it a while longer. The fatigue gradually lessened for me, but it wasn't until I came off of it that I realized it put a damper on my energy in general. I did reach a point, though, where I felt more "normal", so to speak. Give it time.

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well, the only thing is that the regular depakote did NOT make me tired all the time (just at bedtime, which was good because i get wicked bad insomnia), and the only reason the pdoc switched me over to ER was because she couldn't remember why she had me on the regular kind (duh, the insomnia. i swear this woman forgot everything about me between sessions, and had no idea what she was treating me for!). my fault for not calling her back when she left me a mesage saying that's why she switched the type on the rx she called in for me. grrrr i am so tired of being tired.

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I don't want to be a downer here, but the whole time I was on the stuff, I was tired, but not so bad that I couldn't function or anything. In fact I have perpetual sleep issues and Depakote actually improved that a great deal all on its own (which I didn't realize at the time, oddly enough- I suppose I was too fixated on all the negative side effects). I REALLY noticed a difference when I went off it, my insomnia returned big time but I also am so much more awake during the day even with that kind of fatigue, it feels weird to differentiate between sleep deprivation fatigue and drug fatigue, heh heh! But seriously, I'd give it another month then start harassing diplomatically addressing my pdoc about it. ; )

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