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celexa.... how likely is it to induce mania?


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i'm an idiot. finally borke down and took myself to the dr yesterday. i'm currently taking 300mg wellbutrin SR but my depression had escalated to the point i could no longer bear it. lots of crap going on right now with the family.

anyway, dr prescribed an add on AD to the WB. the AD he prescibed is lexapro. this is where the 'i'm an idiot' part comes in.

i was prescribed lexapro last year and it sent me flying high which turned into a bad bad bad mixed state. i was only on the lex for 1 week but the mixed state lasted several weeks beyond that.

but i was too dumbfounded yesterday to tell the dr this year. i took the rx and went to the pharmacy. found out the lex is in the highest tier in my rx plan which i cant afford. didnt fill rx.

i went thru the rx formulary list from my insurance company and i see the the generic for celexa is in the lowest tier, in my price range.

since celexa is the mommy of lexapro, is it liable to do the same thing to me that the lex did last year? or because celexa is less specific than lex, are the chances smaller?

yes, im an idiot. i should have told the dr about the lexapro and i should have never walked out of there with an rx for it. but i was so embarrassed about last year. the only mania/mixed state i ever had was lexapro induced and i dont want to be labeled BP cuz i honestly dont think i am. i just think the lex was just too strong or something. like an adverse reaction.

anyway, it was a sign from god to not take the med when the co-pay was 5 times what i had expected. i dont see the dr again for 2 weeks but i need to call him back and ask for something different anyway, since i cant afford the lex.

anyway, celexa inducing mania????? any thoughts. what are some other options to go with WB that will take the edge off the depression but not send me thru the roof. i dont want to give up my WB cuz it has been wonderful for me. ive just had a lot of personal crap in the last couple of months that was stronger the the WB and me.

thanks in advance.

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I think Lex is the new, improved citalopram, so they both do the same thing. I was recently on a baby dose of citalopram as that's one of the SSRIs least likely to trigger mania (I'm BP). But to be honest, you need to go back to the doc and get all this out in the open.

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Celexa and Lexapro are both SSRIs, so unless you are taking a mood stabilizer (which Wellbutrin is not), either have a really good chance of triggering mania. Lexapro supposedly targets serotonin more selectively than all the other SSRIs. I don't know what that means in terms of BP and potential mania... just thought I'd mention it.

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I went manic after 4-6 weeks on 20 mgs celexa. It could have just been an adverse reaction for you, especially if you are in your late teens or early twenties. It was real mania for me since I could identify manic behavior (undiagnosed) in my past, the celexa just made it into a mixed state from hell. Be very aware of how you're reacting to it this time around (not sleeeping and feeling euphoric were the first signs for me.) Be careful!!

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well, i have 3 weeks samples of the lex from th dr. and cuz im kind of weirding out about the possible whackiness of last year rearing its ugly head again, ive decided to take it but only take 1/2 each day. 10mg is the lowest of the lex and this way i'll be taking 5mg and i can see how it goes. i was too freaked about the 10mg flipping me out again but i wanna try taking it at the lower dose so i can have some time to research other options so when i go see my dr in 2 weeks i'll be more open about everything and together we can deicide the best course of treatment. unless of course the half of lex works for me. thatd be great! ;)

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  • 3 years later...
Guest Kalinka

I had a Celexa induced hypomania 3 years ago. It was a mixed bipolar actuallly. My idiot doctor gace it to me thinking that I had major depression - he has misdiognosed me. But I would like to try it one more time and see how it goes. My life is a little boring since I have quit drinking and I missed the feeling of manic -

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  • 4 weeks later...

I have been on Celexa for years. I've never experienced "manic" from it. It's just not doing the trick anymore. Wondering about adding the Abilify....except people say they have gained weight from it.....that would really be depressing...

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celexa is supposedly the "weakest" of the SSRIs, so even though lexapro is a derivative, the two aren't exactly the same. It's the SSRI my doc said he'd be most likely to use (SMI doc, at that point) if he ever tried an SSRI.

It's one of the least selective ones though, so can have other undesirable effeects. It is more likely to cause fatigue and weight gain (not necessarily to bad if you are worried about mania).

I have tried neither, but what people consistently seem to report is that celexa and lexapro are really NOT similar feeling at all.

A lot of people find they do better at a much lower dose of lex., or ramping it up slowly over time, etc.

Anna

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I was on 40mg of Celexa for 2 years without any side effects. It seemed to work well, but not perfect. After taking it for 2 years, I was hospitalized with mania for 3 weeks as a result. The pdoc said that my mania was a result of taking the celexa. I was stablized with high doses of Seroquel and Depokote. The Seroquel made me extremely tired, so my pdoc took me off of it. I was so tired that I was drooling in the classes at the hospital and could barely keep my eyes open.

When I was released from the hospital, my new pdoc would not prescribe any anti-depressants at all.

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