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Brainfarts on new meds


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I'm taking the meds below.  Most I've started within the last 2 months after getting a new doc for insurance reasons.  With most I've had dose changes and Depakote was just added within the last couple weeks.  My problem is that my memory has gone down the crapper and at least 10 times a day I can't seem to find the word to complete a sentence...like, obvious words.  I'm having brainfarts left and right and I'm hoping this goes away?

I just recently switched around meds from a maintenance dose of a couple things to a higher dose of several meds to try to avoid another manic episode after seeing some signs of hypomania and some very small pyschotic features.  In the past my manic episodes consisted of a LOT of pyshotic features.

I don't want to bore you so much so ask away if I leave out something.  Here's the current list:

Scheduled:

Zyprexa:  20 mg @ night

Depakote:  500 mg @ morning, 1000 mg @ night

Tegretol:  400 mg @ morning, 400 mg @ night

Neurontin:  600 mg @ night

As needed:

Klonipin:  Usually take .5 to 3 mg per day depending on anxiety level

Ambien:  Rarely ever take it since Zyprexa knocks me out  ;)

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i have only taken zyprexa from your list and i was only at 10mg and for the first couple months i felt stupid and like a zombie.  by the third month i was able to think again.  it takes time for body to adjust.  like you, i am currently switching, increasing and dropping medications.  so it feels like as soon as i can function again a med change happens and then it starts all over.  i hope you find the right combo soon, the hardest part is staying with the meds.

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i have taken at one time all of the meds except the as needed ones. the only one that really sticks out in my mind for memory was the neurontin. it seemed like this one messed horribly with my mind in general. i couldn't make it three steps without forgetting where i was going. this was just my experience. ;)

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For the first few days on Zyprexa I was stupid. I couldn't type, was walking into walls, couldn't come up with words. The worst of it wore off about a week into it, but I still have some generic stupidity going on because of god knows which of my meds. The intense stupidity DID wear off, though.

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Depakote was awful for me- brain farts all over the place. It never did get better and I was on it for over a year.

It was really getting to be a problem professionally because I'm a teacher. I'd be up there at the white board talking to the kids and I'd use the wrong word or the wrong tense. I'd start sentences and have no idea how to finish them. Egads!

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I was on 1500 Depakote a day for 5 years; the only other meds at the time were Wellbutrin (needed it to keep my heart beating) and Ambien as needed. 

Depakote knocked my cognition to hell at first, but over a few months I compensated and was able to function pretty normally on it.  As it turns out it had a slight antidepressant effect, which I discovered when I dropped it for Tegretol.  Anyhow, Depakote alone was a great med for me.  I had rare girly problems with it though.

Tegretol has been an awful drag on me (switching to lamictal now), and the 3-4 weeks I once spent on Neurontin I was just dead to the world.  Basically IMHO you're on a real downer of a package.  The changes are recent, so you may adjust and function better in a while. 

Out of curiousity, what's your original diagnosis/mood pattern?  BPI or II?  Or whatever?

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My husband is experiencing some of the same things, he is currently on Depakote 2000mg daily, Wellbutrin 75md daily (started those almost 4 weeks ago) and 3 days ago started Tegretol 200 mg. daily.  Yesterday he "nodded off" as he put it and ran my sportscar into the curb and made a mess of the chrome rims.  UGH!  That was bad, but what if he'd swerved the other way into on-coming traffic?  I think the Depakote is the culprit for brain fogginess w/him.  He says weird stuff like... "put the milk back in the cabinet for me".  HUH?

I'm hoping Tegretol isn't adding to the mix of mixed words, brainfarts as you call them...But he had those things when starting zyprexa, then they faded off and were replaced by a complete lack of caring for anything on the planet except eating.  Good luck!

Kim

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