Cetkat Posted September 27, 2007 Share Posted September 27, 2007 Alright, so right now I'm on what's in my sig line. I have depression that simply will not go away, and has actually gotten worse. Prior to this, Cymbalta helped and I could still think straight. Now Cymbalta doesn't do what it once did, and I'm on the stimulant for augmentation and concentration - which I now really need. The norepinephrine inhibitor in the Effexor exacerbated my anxiety, but its serotonin effect makes it work a little bit like the Cymbalta did. The stimulant doesn't really make me anxious. So I desperately need something else and would love any suggestions/comments on what else to try. 1. I haven't been on any TCA's. Pdoc says there would be no point in trying them since they work alot like Effexor... but Cymbalta was my best med. Is he right, or should I try them anyway just in case? 2. Other than Cymbalta; Lithium and Lamictal made the most impact. Lithium is now ineffective without a working Cymbalta, and Lamictal's side effects made my depression worse.. but the med part of it worked at first. This makes me think a mood stabilizer would be good. So I plan on mentioning the GABA meds like Neurontin, and even trying Lamictal again with an emphasis on mitigating the side effects. Any thoughts on this? Also.. would Depakote or Topamax be worth trying? I want to raise the floor on my mood, but I don't have any mania to speak of to even out. 3. The pdoc mentioned adding a Thyroid med. I have no problems with that. 4. The only other things I can think of on this front are Mirapex (dopamine), Buprenex (opiate), Ultram (opiate/nor/ser), and BuSpar (augmenter). 5. If nothing else works, I'm going to try Ensam => other MAOI's => ECT So.. am I missing anything? Any other treatments to consider; and also, what should I try first? I'm not going to get any more benefit from what I'm on, and I need to come up with a treatment plan for my next appt. Edit: Title Link to comment Share on other sites More sharing options...
This topic is now archived and is closed to further replies.