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Hi,

I just recently began Lyrica, titrating up to 300mg last night. My current cocktail already consists of Lithium, Lamictal, Topamax, Cymbalta and Seroquel & Trazadone as PRNs. Now, I can deal with side effects. I have dealt with side effects. I am a walking ad for side effects. But, I cannot tolerate "a lot" of weight gain. I want to know what this means, what this entails, and what your experience has been.

Thanks,

Victoria

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Wow, lots of Lyrica discussions today! I've been on 50 mg tid for well over a year and no weight gain. It works well on my pain and anxiety with a side effect of just a little sleepiness. Hope this helps.

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I was on Lyrica recently for anxiety (it's officially approved for that over here in Europe). On 300 mg, I gained 2 lbs a week for the 2 months I took it. It seemed very dose-dependent for me though, when I went down to 150 mg I immediately lost that extra appetite. I also lost 4 lbs in about 2 days while still eating, so some of that must have been retained fluid. I still went off Lyrica completely because the effect/side effect ratio for me didn't make it worthwhile. After stopping it, I have gradually lost some of the weight I put on, without actually dieting.

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I was on Lyrica recently for anxiety (it's officially approved for that over here in Europe). On 300 mg, I gained 2 lbs a week for the 2 months I took it. It seemed very dose-dependent for me though, when I went down to 150 mg I immediately lost that extra appetite. I also lost 4 lbs in about 2 days while still eating, so some of that must have been retained fluid. I still went off Lyrica completely because the effect/side effect ratio for me didn't make it worthwhile. After stopping it, I have gradually lost some of the weight I put on, without actually dieting.

I am hoping that by continuing (and ramping up) a large water intake regime, I can avoid a lot of fluid retention. I will take from your post to be mindful about the appetite increase (very scary for me) and hope that the benefits DO outweigh the side effects.

I appreciate the input from both of you!

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