Greenyflower Posted October 7, 2007 Share Posted October 7, 2007 I had been on Zoloft at 50 mgs, in conjunction with Wellbutrin XL at 450 mgs, for 2 1/2 years when I started slipping back into depression. The Zoloft has now been upped to 150 mgs not quite three weeks ago. I've not noticed much benefit, but my hand tremor has increased exponentially. The minimal benefit I have noticed is better sleep; other than that, nada. I'm not sure whether to try the Zoloft at 200 mgs or try something new along with the Wellbutrin. Have any of you experienced a significant beneficial difference between 150 & 200 mgs of Zoloft for depression and also persistent and intrusive thoughts? My next pdoc appointment is on November 1st. Link to comment Share on other sites More sharing options...
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