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Key Messages Derived From Literature Review of Antiepileptic Drugs (AED) Treatment for Bipolar Disorder

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University of North Carolina's Prescribing for Better Outcomes Center issued its findings concerning the use of anti-seizure drugs in bipolar disorder, types I and II.

No scientifically acceptable clinical trial evidence supports use of either gabapentin or topiramate in bipolar mood disorder, either as monotherapy or as an adjunct to other therapies.

Research supports use of three antiepileptic drugs

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