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bi-polar gene?

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Sounds like there is a lot more work to be done.

"These two genes probably have modest effects and each is involved in only a few cases of bipolar disorder, Dr. Craddock said. But they and other genes yet to be found may point to the underlying biology of the disease, which may affect a much larger number of patients."

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In my family, we seem to have an extremely autosomal-dominant penetrating gene mutation, whatever it is. I'm going to call it guano1, whose receptor product will be known as Batshit.

Hilarious! hahahahaha. I freakin' love it!

I recently read an article from the prominent science publication Yahoo! News also dealing with Bipolar genes. It said the gene they found that was affected interfered with the transportation of calcium and sodium to channels in the brain. The information was taken from the journal Genetics.

Two genes that influence the activity of nerve cells in the brain may play a key role in a person's risk for bipolar disorder, marked by dramatic swings from depression to manic behavior, researchers said on Sunday

.......The researchers found those with bipolar disorder more likely to have certain variants of the ANK3 and CACNA1C genes. Proteins made by the two genes help govern the flow of sodium and calcium ions into and out of neurons in the brain, influencing the activity of these nerve cells.

Link to the article: http://news.yahoo.com/s/nm/20080817/hl_nm/bipolar_genes_dc_1
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