Guest Posted January 29, 2009 Share Posted January 29, 2009 Link to comment Share on other sites More sharing options...
CrazySoprano Posted January 29, 2009 Share Posted January 29, 2009 Do you actually *feel* manic, or is it just that you haven't felt normal in so long that normal feels manic? Have you ever had bipolar symptoms before? I know that Wellbutrin is one of the few antidepressants that BP's like because it's less likely to cause a mixed state than SSRI's. It's probably the most activating AD out there, so I can understand how you'd feel an immediate response. I tend to feel a little jittery a couple hours after I take mine. WB is still my favorite antidepressant. It works better for me than anything else. I hope it works for you! Link to comment Share on other sites More sharing options...
Velvet Elvis Posted January 29, 2009 Share Posted January 29, 2009 It's kinda stimulating and kicks in pretty quick. It's not unusual to feel something speedy the first few days. If it's more than you'd get off a few cups of coffee there might be a problem. It should mellow out during the first week. Link to comment Share on other sites More sharing options...
AnneMarie Posted January 30, 2009 Share Posted January 30, 2009 Sylvan, If I was you and it messed with my sleep, I'd call my doc tomorrow instead of taking more. The 100mg immediate release might work better. I'd also talk to your doc about Mirapex. It plays with dopamine in a different way. It works well for some, but not for all. SSRIs are horrible experiences for me. Same with SNRIs. Wellbutrin probably is too strong. Mirapex, however, works well at a lower dose. For me, it's a truly wonderful med. Link to comment Share on other sites More sharing options...
CrazySoprano Posted January 30, 2009 Share Posted January 30, 2009 The SSRI's that I've tried have all made me manic in a matter of days. If Wellbutrin is more activating than the SSRI's then I may be in trouble. If it stays at this level, I can handle it. I should explain that WB isn't activating in a manicy kind of way. It's more likely to be a problem for someone prone to anxiety. VE is right--for me, it usually feels like I had too much coffee, then mellows out after a while. It might be a start-up side effect for you, maybe something that will always happen. Remember, feeling good is a *good* thing, even if it's not what you're used to. Link to comment Share on other sites More sharing options...
olga Posted January 30, 2009 Share Posted January 30, 2009 I'd keep taking it if I were you. I think you need to give meds at least a couple of weeks to judge their effect. When I started with Wellbutrin, I was out on my property cutting brush and weeding the asparagus patch and leaping tall buildings in a single bound. heh Loved it. But that wore off after about 3 or 4 days and I was back to my version of "normal." Except I wasn't depressed anymore. Stick with it. You might be very happy with it. olga Link to comment Share on other sites More sharing options...
Caillech Posted January 30, 2009 Share Posted January 30, 2009 Wellbutrin put me in a mixed state from hell the whole two months I was on it. But as usual, ymmv. SSRI's in general are bad news for me also, unless I'm on a mood stabilzer. I vote with the others. Give it a fair chance. Link to comment Share on other sites More sharing options...
CrazySoprano Posted January 30, 2009 Share Posted January 30, 2009 Sometimes you have to futz with the timing for Wellbutrin. Which flavor are you taking? Immediate release, SR, or XL? Are you taking the name brand or the generic? If taking it in the morning keeps you up all night, try taking it before you go to bed or in the afternoon. Another fun thing about WB, for me at least, is that it makes me want to have sex. All. The. Time. I keep taking the Lexapro so I won't go out and start humping everything in sight. Link to comment Share on other sites More sharing options...
lysergia Posted January 30, 2009 Share Posted January 30, 2009 I'm taking Wellbutrin XL, name brand. My psyMD wouldn't let me take the generic. He said he'd had too many problems with it in the past. smart psyMD! I took another one this morning and it feels pretty much like it did yesterday. I can take on the world. I've got my diet/eating under control and I'm actually getting a little exercise. This really is an amazing drug. if memory serves me correct i felt almost high for a little while at first. but it was sluggish high, like opiates or something. however, the mood change was LOVELY. it did settle in after a few weeks and i didn't feel high or tired anymore. my motivation level, however, did stay exceedingly high when compared to my pre-WB state! I haven't noticed wanting to have sex. I haven't wanted to have sex for a couple of years. If Wellbutrin will fix that I'd be thrilled, and so would my husband. i did help mine, but not instantly. it was more like i felt better over time, so wanting sex (and other pleasures!) was a natural extension. i wasn't so anhedonic that nothing felt good anymore. that was also a huge and very welcome change. stay on it for a little while to see what it feels like after the "high" stage. good luck Link to comment Share on other sites More sharing options...
mejeba Posted January 30, 2009 Share Posted January 30, 2009 The first day I took WB XL, 150 mg, I became immediately energized. It was great. I couldn't believe that a single dose would work like that. The dragging on-and-on depression started to lift right away but I still had lots of anxiety, and my pdoc was actually targeting anxiety with this, so he raised it to 300 mg. After that, I was mildly high for months. What a relief! It finally settled down in the Fall, but I've been pretty mixed since then. Anxiety is bad, but I don't fault WB for that. Winter and stress is bringing me down hard. I wouldn't want to give this one up. In fact, I wouldn't mind upping the dose. Link to comment Share on other sites More sharing options...
fluffybirdie Posted January 30, 2009 Share Posted January 30, 2009 I've been on it for 2 years. When I first started, I was a total speed-racer for a week. It wasn't bad manic, just sorta funny, but it does mellow out. But it did take at least a week. I'd stick with it, it's a good drug. I've been on lots and am pretty jaded with some, but the WB is a keeper. Any chores or such that you may have been putting off, do them now! hehe Link to comment Share on other sites More sharing options...
AnneMarie Posted January 30, 2009 Share Posted January 30, 2009 Hey Sylvan, That's good news! If you're sleeping fine w/no signs, enjoy the extra energy!! Link to comment Share on other sites More sharing options...
Reborn Posted February 11, 2009 Share Posted February 11, 2009 Wellbutrin is one of the common drugs prisoners try to crush up and inhale to get high. It can definitely make people high, but it has that nasty little seizure side effect at the doses that would normally make someone high. That's kind of a deterrent. The stuff was like speed for me when I first started taking it. I literally could not stop shifting my weight for 2-3 hours after taking each pill. Within a month it started to balance out though. After awhile, it was about as stimulating as drinking a Pepsi - nothing bad. Link to comment Share on other sites More sharing options...
Beetzart Posted February 15, 2009 Share Posted February 15, 2009 Can you get Wellbutrin in the UK for depression? I think it is called Zyban for smoking cessation but not sure if it is used as an AD though. Link to comment Share on other sites More sharing options...
scatty Posted February 15, 2009 Share Posted February 15, 2009 Wellbutrin always helps me out of the deep, suicidal depressions I get. It is fast acting for me. Within days I see a difference. I'm BP so I often swing the other way after a few months and have to discontinue it. It is always there if I need it again, which is comforting. I haven't needed an AD for a while now, thankfully. Link to comment Share on other sites More sharing options...
mejeba Posted February 20, 2009 Share Posted February 20, 2009 Can you get Wellbutrin in the UK for depression? I think it is called Zyban for smoking cessation but not sure if it is used as an AD though. My understanding is that Zyban is a completely different drug. Link to comment Share on other sites More sharing options...
Velvet Elvis Posted February 20, 2009 Share Posted February 20, 2009 Zyban and Wellbutrin-SR are the same thing Link to comment Share on other sites More sharing options...
Guest Benoibe Posted October 13, 2010 Share Posted October 13, 2010 I am experiencing the same thing. I am on lexapro and just upped wellbutrin xl to 300mg today. I feel high as a kite. I know this won't last. I feel like I'm on speed of some sort. Not anxious. But very talkative and just sped up. My Dr warned me that it makes some people feel like this in the beginning. So Im hanging in there. You should too. I'm not bipolar, but i definitely feel manic. It will pass. Wellbutrin has seems to be one of best antidepressant-add-ons out there. I've read where many people eventually taper off their 1st AD med and just take this. I am definitely no expert, but all the research I've done makes me very hopeful about this med. Many other ADs have not worked and left me discouraged. Good Luck. Link to comment Share on other sites More sharing options...
confused Posted October 13, 2010 Share Posted October 13, 2010 I am experiencing the same thing. I am on lexapro and just upped wellbutrin xl to 300mg today. I feel high as a kite. I know this won't last. I feel like I'm on speed of some sort. Not anxious. But very talkative and just sped up. My Dr warned me that it makes some people feel like this in the beginning. So Im hanging in there. You should too. I'm not bipolar, but i definitely feel manic. It will pass. Wellbutrin has seems to be one of best antidepressant-add-ons out there. I've read where many people eventually taper off their 1st AD med and just take this. I am definitely no expert, but all the research I've done makes me very hopeful about this med. Many other ADs have not worked and left me discouraged. Good Luck. I felt the same way when I started wellbutrin. It went away pretty quickly. Link to comment Share on other sites More sharing options...
water Posted October 13, 2010 Share Posted October 13, 2010 I am experiencing the same thing. I am on lexapro and just upped wellbutrin xl to 300mg today. I feel high as a kite. I know this won't last. I feel like I'm on speed of some sort. Not anxious. But very talkative and just sped up. My Dr warned me that it makes some people feel like this in the beginning. So Im hanging in there. You should too. I'm not bipolar, but i definitely feel manic. It will pass. Wellbutrin has seems to be one of best antidepressant-add-ons out there. I've read where many people eventually taper off their 1st AD med and just take this. I am definitely no expert, but all the research I've done makes me very hopeful about this med. Many other ADs have not worked and left me discouraged. Good Luck. I felt the same way when I started wellbutrin. It went away pretty quickly. Ditto Link to comment Share on other sites More sharing options...
kariered Posted November 20, 2010 Share Posted November 20, 2010 When the Wellbutrin SR I take started to kick in, I admit, I did feel pretty high for several days. Almost like when I took X about 10 years ago...almost. It did wear off and now I do feel pretty normal, but not nearly as depressed. Link to comment Share on other sites More sharing options...
etkearne Posted November 21, 2010 Share Posted November 21, 2010 I had that feeling for four days on Wellbutrin. Then it stopped. I never considered it a high, but more of what life is probably like for normal people. It never seemed manicy. It was clear, focused, etc., not erratic, volatile, etc. I am now on Adderall, which shares a similar "feel" to the first four days of Wellbutrin, except it doesn't randomly poop-out. Both work on norepinephrine and dopamine. I highly suspect that those two neurotransmitters in in more disarray than serotonin for me. SSRI's never did anything. At all. And, Effexor only works over 225mg per day, which happens to be around the threshold for norepinephrine modulation in that drug. Link to comment Share on other sites More sharing options...
Guest cheetos Posted November 22, 2010 Share Posted November 22, 2010 I just got my dosage upped to 450mg and I do feel off like I'm "high" or something. Not a pot high but like a cocaine high (I'd imagine) It's kind of creeping me out. Link to comment Share on other sites More sharing options...
DKnight Posted November 22, 2010 Share Posted November 22, 2010 I always just felt jittery and nervous on it. Wasn't on it long though. Only a week so I didn't give it a fair chance. However the first night I took it I felt "normal" like what I imagine most people feel like or should feel like. A normal motivated good feeling state of mind. Link to comment Share on other sites More sharing options...
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