notfred Posted October 4, 2009 Share Posted October 4, 2009 From the Biovail web site: Wellbutrin XL ® Launched in the U.S. by GlaxoSmithKline (GSK), in September 2003, Wellbutrin XL®, an extended-release formulation of bupropion indicated as first-line therapy for the treatment of depression in adults, was well received by U.S. physicians and by the end of 2006, had captured 59% of all bupropion prescriptions in the U.S. Pursuant to Biovail’s manufacturing and supply agreement with GSK, the Company received a tiered supply price that was based on GSK’s net sales of Wellbutrin XL® in any given year. However, as a result of the May 2009 acquisition of full U.S. rights to Wellbutrin XL® , Biovail will now record 100% of U.S. revenues from the product. In January 2007, GSK announced the first European approval for Wellbutrin XR® (the brand name that GSK will use in a number of countries for our once-daily formulation of bupropion hydrochloride) in The Netherlands for the treatment of adult patients with major depressive episodes. Since then, Wellbutrin XR® has been launched in a number of European countries, including Germany, Italy, Spain, Sweden, Netherlands, Norway, Austria, Iceland, Poland, Portugal and Greece. Biovail manufactures and supplies Wellbutrin XR® to GSK at fixed contractual supply prices. According to the Orange Book GSK still makes Wellbutrin and Wellbutrin SR and only Biovail makes Well butrin XL. Link to comment Share on other sites More sharing options...
MarkP Posted October 5, 2009 Share Posted October 5, 2009 Yeah and buproprion was invented by Burroughs Wellcome. What's the issue here?? Link to comment Share on other sites More sharing options...
notfred Posted October 6, 2009 Author Share Posted October 6, 2009 Yeah and buproprion was invented by Burroughs Wellcome. What's the issue here?? General interest. I understand the look of the pill will change, so it is FYI. Sometimes when a brand is sold it it is not the same/as effective or just different when made by the new manufacturer, as in the case with Nardil. On a postive note, Biovail is also coming out with a generic of the XL, too. Some people, like myself, did not do well when switched to the generic and can only take the brand. Sometimes when the same company makes the brand and generic there is really no difference (same binders and fillers) between the two except appearance. nf Link to comment Share on other sites More sharing options...
Stonum Posted October 6, 2009 Share Posted October 6, 2009 Hi, I'm new here with making comments. I have taken a lot of medications. Yes,I believe that brands differ. Some have thinner or thicker coatings, etc I don't think that XL is as time released as doctors say. I was on 450mg all at once in the morning. I was in the most part going delusional till mid day. Yea, I was higher than I should have been. Then came the crash. To make a long story short, I was hospitalized. I'm still paying for that. Sincerely, Stonum Link to comment Share on other sites More sharing options...
notfred Posted October 6, 2009 Author Share Posted October 6, 2009 Hi, I was on 450mg all at once in the morning. Wow. 300 mgs is the max dose to take at one time according to the Prescribing Information. nf Link to comment Share on other sites More sharing options...
Stonum Posted October 6, 2009 Share Posted October 6, 2009 Hi again, Well it was 450mg all at once. I got hypo manic. Some neighbors called the police. I was put on a police hold. I wasn't even under arrest. I went to the Johnson unit in Eugene. I broke down their security door which they called criminal mischief. The maximum penalty for C.M. is five years. My attorney said I should Plead guilty except for insanity. He said I might do three months? I did the five years. now I'm paying for other simmular situations. Sincerely, Mark Link to comment Share on other sites More sharing options...
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