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It's always smart to only change one med at a time so that you can figure out what is doing what. Also, if you are having problems with your meds, the best person to work that out with is you pdoc. Does your pdoc have an opinion about which med might be making you feel unwell?

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The PI sheet recommends a starting dosage of 750mg divided into two doses. So, your dosage is below that. You might consider splitting it morning evening. Taking it with with food may help if it is upsetting your gut. What symptoms are you having?

Hope you feel better. a.m.

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