steves Posted November 27, 2009 Share Posted November 27, 2009 well my doc has switched me from geodon to seroquel xr 300mg taken twice. His directions say take twice a day but everything i read says take once a day. I dont want to start getting too much cause my doses are overlapping. They did this to me with lithium er told me to take 3 seperate doses and i became toxic. i mean even the seroquel website says once a day dosing 3-4 hours before bed time. Anyway anybody split there dose are has any one heard of split xr doses? Link to comment Share on other sites More sharing options...
tryp Posted November 28, 2009 Share Posted November 28, 2009 I split my dose, but it's not all XR - I take 150 mg IR at night and 100 XR in the morning. It could be that your doc is trying to reduce the sedation or something... Link to comment Share on other sites More sharing options...
Silver Posted November 28, 2009 Share Posted November 28, 2009 The Seroquel XR is usually once a day, you're right. But since you cite "constant mania" in your sig, perhaps he's trying to get you better coverage? Why not ask him? He also may just be in the habit of writing for Seroquel regular as a twice per day drug. Side note - As to lithium CR/ER as a three-times-per-day dose making you "toxic" - lithium level is really a function of the total daily dose, rather than whether or not it's spread out throughout the day. Some people do best with their dose broken up (usually for GI reasons), many do best with once-per-day dosing, whatever. I'm just throwing this gratuitous pedantry in here to keep people from unnecessary anxiety about their three-times-per-day lithium dosing. Link to comment Share on other sites More sharing options...
Psylocke Posted November 30, 2009 Share Posted November 30, 2009 I was told by the pharmacist to not split Seroquel in half. It even states that on the main seroquel webpage. Not sure what it does when you split it. I would say your best bet is to contact your doctor and question why you are on a high dose. I was started out 2 days ago on 150mg and people are telling me that is a high dose. Hope you get the answers you need Link to comment Share on other sites More sharing options...
Aanga Posted December 3, 2009 Share Posted December 3, 2009 I've been taking Seroquel XR for a good chunk of the year and my doctor split the doses. My dose was 100mg at night and 50mg in the morning. Low dose, but we're still in the figuring out stages of my meds and seeing how my body reacts to all of it. Link to comment Share on other sites More sharing options...
an-dree-yuh Posted December 3, 2009 Share Posted December 3, 2009 When i first started taking XR my dose was split in half as well. I believe when it says not to split it, it means not to cut the pills in half. the reason it's like that is because it's extended release, and cutting the pill in half would mess with the actual dosage. i was taking 600mg XR a day split into two 300mg doses. Seroquel is a fairly high dose medication so it's normal to have such a large amount. if it's really bothering you I would just talk to my doc about it.. Link to comment Share on other sites More sharing options...
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