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Appointment with the ladydoctor finally came around but my hopes of any easy fix didn't happen. She said it's a tricky case so she said she would consult with pdoc, sent me away with a few options and instructions to call in a week and tell her what I decide. Also wasn't certain that the progesterone was the culprit in the Yasmin disaster.

The options:

1) Try a lower dose birth control pill like Yaz.

2) Get an Implanon. Less invasive than the Mirena but it looks like it worsens depression for 5.5% of people.

3) Get a Mirena. (6.4% experienced worse depression)

4) Possibly add another AD (ladydoctor didn't elaborate but I'm hesitant to change the amitryptaline)

5) Start on a mood stabilizer (this was pdocs idea, possibly Lamictal)

Does anybody have any advice on what may work? I've been reading some of the meta reviews and it's a little dismal. Doing nothing isn't an option.

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I've never had the official PMDD label, but I've had some shitty moodiness around that time - beyond the norm. I take Lamictal and Abilify and they help a little, but an AD is what finally made a big difference. I get the mood stabilizer intuition - PMDD and other cyclical depressions are freakishly like BP disorders. But I wonder if PMDD is more of a serotonin issue. If I recall correctly, it's thought that serotonin levels drop around that time of the month (That's why a lot of women get carb cravings - boosts serotonin).

I take Effexor XR. I'm a fan. Hits more serotonin than Elavil, from what I understand.

As for hormonal options - blargh. I couldn't take hormonal birth control pills for a long time because they fucked with my mood too much. I can tolerate Ortho-Novum 7/7/7 for whatever reason. Ortho-Novum 1/35 was OK, too. The low low dose pills, Yasmin, and the Nuva Ring made me a train wreck. Not sure why that is. The joys of funky brain chemistry, I suppose.

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  • 4 months later...

Appointment with the ladydoctor finally came around but my hopes of any easy fix didn't happen. She said it's a tricky case so she said she would consult with pdoc, sent me away with a few options and instructions to call in a week and tell her what I decide. Also wasn't certain that the progesterone was the culprit in the Yasmin disaster.

The options:

1) Try a lower dose birth control pill like Yaz.

2) Get an Implanon. Less invasive than the Mirena but it looks like it worsens depression for 5.5% of people.

3) Get a Mirena. (6.4% experienced worse depression)

4) Possibly add another AD (ladydoctor didn't elaborate but I'm hesitant to change the amitryptaline)

5) Start on a mood stabilizer (this was pdocs idea, possibly Lamictal)

Does anybody have any advice on what may work? I've been reading some of the meta reviews and it's a little dismal. Doing nothing isn't an option.

Thanks you for the post.

_________________

Watch The Karate Kid Online Free

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  • 2 weeks later...

I know that when estrogen rises, serotonin drops, which is prob why they suggested a low-dose (lower estrogen/progesterone) pill and/or mood stabilizer and/or AD (my pdoc said that I'd just augment my normal meds routine for a few days with the additional AD).

I don't know anything about Mirena or Implanon.

As for the augmenting with more of the same AD/a different AD, I need to chart my months more carefully first, so I know exactly what days I would need to take them.

That's my experience with all this nastiness.

yeah me too, I don't know anything about Mirena or Implanon.

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  • 3 months later...

It's been a while since this original post, but thought I'd add that I spent a couple of years going down this road and finally settled on Danazol. Your doctor may go "Huh?" if you mention it - it's pretty old-school (formerly used to treat uterine bleeding). It has completly stabilized my mood. No menstrual cycle. I had hoped it would help with the migraine, but alas, no luck on that front.

I've been on it a little over a year. Just got a second opinion about the treatment from another doctor. 200 mg every other day with 100 mg of Aldactone to keep me from turning into a man.

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  • 2 weeks later...

Hello. I am a newbie here, but I have been diagnosed with PMDD and I tried Zoloft, did nothing for the 2 wks prior to my period rages. My Gyn suggested I try Yaz but I decided to go with Prozac and give that a shot first. I cannot tell you if it has helped bc I just started taking it 4 wks ago. I chose to go with Prozac bc I would like to stay away from birth control, but if it all comes down to needing it, then I will take it. Good Luck with your choice and I hope whatever you choose helps!

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Hey, welcome Nikki.

SSRIs have the most evidence for helping with PMDD (more than BC) so it's worth trying another one. I hope it works for you.

As an update lamictal didn't work so under the advice of an endocrinologist I'm (very tentatively) trialing another BC pill. Waiting until exams are over.

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Thanks! Yea, I read up on Prozac and brought it up to my counselor and together we decided to talk to my pdoc about it, and she started me on it. I hope this is it bc my PMDD really is my biggest problem, I hate it. I hope your new med works as well :)

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