HyperInHell Posted August 30, 2005 Share Posted August 30, 2005 Anyone know of a good antipsychotic that does not cause weight gain? I am already heavy enough. Link to comment Share on other sites More sharing options...
Kablume Posted August 30, 2005 Share Posted August 30, 2005 Zyprexa and Seroquel cause the most. The one I do not know about is Abilify. Hopefully someone who has been on it could tell you. Link to comment Share on other sites More sharing options...
Sulu Posted August 30, 2005 Share Posted August 30, 2005 FWIW, I have heard that risperdal is supposed to be weight-neutral. Sulu Link to comment Share on other sites More sharing options...
foreverpondering Posted August 30, 2005 Share Posted August 30, 2005 I'm currently on abilify and it is pretty much weight neutral, in fact i have actually lost a few pounds (around 5 in a month). I have had some activation which has actually allowed me to resume my workout regime. I would definitely be willing to recommend this med. Link to comment Share on other sites More sharing options...
Panz Posted August 30, 2005 Share Posted August 30, 2005 I'm taking Effexor and Seroquel, Seroquel makes my starving all the time...like wrestle the dog for it's kibbles hungry, but the Effexor makes me not hungry, so I'm not doing to bad on that mix. I was on Zyprexa for three weeks and gained 11 pounds ...I hope that eventually they can jiggle with the meds enough to bar that side effect Link to comment Share on other sites More sharing options...
jmb252 Posted August 30, 2005 Share Posted August 30, 2005 Abilify and Geodon both tend to be weight-neutral. Seroquel can be a big gainer for some, but for others is neutral. Risperdal also, though generally less of a gainer than Seroquel. Zyprexa is almost guaranteed weight gain. Of course, the main thing is to treat the problem. Not all APs will be certain to cause you weight gain, but they also might not help whatever the problem at hand is. When you talk to your doctor about adding an AP, make sure he or she knows that you are concerned about weight gain. Good luck, jen Link to comment Share on other sites More sharing options...
chimpmaster Posted August 31, 2005 Share Posted August 31, 2005 Abilify has the best reputation, zyprexa the worst, and the rest are somewhere in between. Remember they do different things as well though. Abilify is quite activating whereas zyprexa and seroquel are calming drugs. I found with seroquel i gained for the first month, but now its levelling out, i hope. I have heard good things about abilify though, so long as it doesnt give you insomnia and agitation. Link to comment Share on other sites More sharing options...
scarlet_faery Posted August 31, 2005 Share Posted August 31, 2005 Ha! Don't make me laugh! I have gained weight on all of them. You're all lucky. Try being plus size in the first place then adding one of these drugs and gaining 20 to 30 pounds in a month or less. I never win. NEVER! Link to comment Share on other sites More sharing options...
tigrre Posted August 31, 2005 Share Posted August 31, 2005 Do all antipsychotics cause weight gain? for me... yeah pretty much then again I'm just lazy and fat anyway... I have a crappy diet and eat whatever and whenever I feel like it... Link to comment Share on other sites More sharing options...
JustAPrettyDrug Posted September 4, 2005 Share Posted September 4, 2005 Anyone know of a good antipsychotic that does not cause weight gain? I am already heavy enough. <{POST_SNAPBACK}> Risperdal is supposed to be weight neutral. However stuff like Seroquel and the others are only a problem (according to what I have read) if you are on a medium to high dose of it for a long time. Link to comment Share on other sites More sharing options...
JustAPrettyDrug Posted September 4, 2005 Share Posted September 4, 2005 Do all antipsychotics cause weight gain? for me... yeah pretty much then again I'm just lazy and fat anyway... I have a crappy diet and eat whatever and whenever I feel like it... Link to comment Share on other sites More sharing options...
sun_zoom_spark Posted September 4, 2005 Share Posted September 4, 2005 I gained weight on Zyprexa but not on Seroquel or Abilify. I also was not watching what I ate when I was on Zyprexa. I was on a diet while on Abilify and now on Seroquel. I think it's basically up to the individual but APs probably won't mess with you too much if you remain disciplined. These drugs really demand a lifestyle change if you haven't already made one. Sorry if I come across as 'preachy' but it is true. Link to comment Share on other sites More sharing options...
sdjeff Posted September 4, 2005 Share Posted September 4, 2005 Zyprexa was a huge gainer for me. I'm on Risperdal now and I've actually lost weight. Link to comment Share on other sites More sharing options...
tigrre Posted September 4, 2005 Share Posted September 4, 2005 Are you sure you guys just don't have eating or exercise problems as it is <{POST_SNAPBACK}> yes I'm certain I have eating and exercise problems, they just seem to get exacerbated when I'm initially put on most APs. I can stay at a stable weight otherwise but I'm certainly not a model of fitness or healthy eating normally. Link to comment Share on other sites More sharing options...
stinky Posted September 5, 2005 Share Posted September 5, 2005 Are you sure you guys just don't have eating or exercise problems as it is <{POST_SNAPBACK}> this is unfair. all antipsychotics are known for weight gain. it is thought to be mediated through histaminergic receptors. yes, it's pissy that they can't make drugs that are side effect free, but don't forget that these are drugs that are made for people with serious, debilitating, life-threatening mental illness and crappy treatment is better than no treatment, and there aren't really many other options. otherwise clozapine would be off the market. Link to comment Share on other sites More sharing options...
cabal Posted September 5, 2005 Share Posted September 5, 2005 Anyone know of a good antipsychotic that does not cause weight gain? I am already heavy enough. <{POST_SNAPBACK}> Risperdal and Abilify tend to be fairly weight neutral. For most people, Seroquel is (nearly) weight neutral. But I've read that if it makes you gain weight, it makes you gain A LOT of weight. I'm not sure of that, though. Most of the typical/classical antipsychotics are weight neutral. I don't know much about them. But maybe haldol would be a good candidate. The newer antipsychotics aren't always better. Link to comment Share on other sites More sharing options...
Bohemian Posted September 5, 2005 Share Posted September 5, 2005 It's all in what you do. I take 30mg of Zyprexa, 15mg of Abilify and 8mg BID of Perphenizine (old school antipsychotic), and I have lost ten pounds in the last month. Exercise helps! You can beat the weight gain of these antipsychotics, I have. Best, Chris Link to comment Share on other sites More sharing options...
MoparGuy1991 Posted September 5, 2005 Share Posted September 5, 2005 Yeah, with Seroquel, as you mentioned, it generally doesn't cause weight gain for most. However, when it DOES happen, it can be just as bad as Zyprexa. I took up to 100mg of Seroquel for less than a week and never noticed any increase in appetite nor weight. I took it for sleep, but it didn't keep me asleep through the night as expected, and I was at the most sedating dosage ranges (which are the lower dosages). With Abilify? not so sure but probably gained some. I took up to 5mg of that recently. I took it with 100mg of Luvox. During the period of taking both, my appetite was pretty large but seemed to go back down when cutting back on Luvox and Abilify. I gained about 4-5 lbs in several weeks, I think. Not sure if I could pinpoint it to Abilify or not, but pointers go to Abilify maybe. I tended to lose some weight with Geodon on each trial. On 1st trial, 10 lbs. On 2nd trial, 8 lbs. Zyprexa, which I took for 1 month at 15mg, I gained maybe 10 lbs. Here's the think about the Zyprexa, though. Initially, I used samples for the 1st week. They were the Zydis form (dissolvable). With that form, I didn't gain any weight for first week. When I switched to regular tablets, appetite went up and the weight came on. Strange. Link to comment Share on other sites More sharing options...
Sulu Posted September 6, 2005 Share Posted September 6, 2005 Just wanted to mention that age and state of physical health probably has somethiing to do with possible weight gain. Link to comment Share on other sites More sharing options...
Caillech Posted September 15, 2005 Share Posted September 15, 2005 Not much hope here. I have been on Risperdal for almost two months. While I love the way it helps whatever is wrong with me, I have gained 20 lbs. Thats 10 pounds a month. I am demanding to be taken of this drug on monday. Id rather swim thru depression and hypomania than weigh 250 pounds. At that point Id be sooo depressed id try to kill myself, again. I took seroquel with no weight gain issues. But it makes me anxious and jittery. I wont try any other ap after this cuz I refuse to gain another pound. Good luck Link to comment Share on other sites More sharing options...
antipeople Posted September 16, 2005 Share Posted September 16, 2005 Risperdal made me gain about 5lbs. I've been taking it since February. Link to comment Share on other sites More sharing options...
ZoeGurl Posted September 21, 2005 Share Posted September 21, 2005 I have been on 3mgs of Risperdal for over a year now, and it works awesome, but I have gained quite a bit of weight. Link to comment Share on other sites More sharing options...
SerraGeorge Posted October 1, 2005 Share Posted October 1, 2005 I've taken Zyprexa a few different times. The first was right before my wedding. I was not informed as to the weight gain side effect, and was shocked to find that on my wedding day, my gown alterations were null and void. I didn't know why it didn't fit anymore... just that it didn't. (Fortunately, my mom makes a pretty good emergency seamstress!) Anyway.. the last time I tried it, I was much more attentive to side effects. I gained about 15 pounds in a month. As best as I can tell, it was attributed to two things. The first being that the Zyprexa worked. I slept. I stopped fidgeting all over the place. I was able to be still. The second was the need for cake. I literally found myself watering at the mouth over cravings for bread, pasta, cake, pie... anything carb, and I *needed* it. It was the strangest feeling, as I have always been an eat to live type person. I typically find the act of eating to be a chore. The Zyprexa activated raging primal cravings that were very difficult to appease. I was happy with the way the drug was working, and didn't care about the weight gain, but pdoc did. Zyprexa got taken away from me. Link to comment Share on other sites More sharing options...
Shakespeare Posted October 9, 2005 Share Posted October 9, 2005 Here's the official pecking order: Patients gaining greater than 7% of their body weight- Abilify 8% Geodon 10% Risperdal 18% Seroquel 23% Zyprexa 30% BUT here's the more interesting stuff... after one year patients had gained an average of- Abilify/ Geodon 1kg Risperdal 2-3kg Seroquel 3.6kg Zyprexa OVER 10kg (doses 10mg-30mg, about 6kg for smaller doses) That being said, I gained almost 30 lbs on Abilify. In practice it seems to be kind of a coin toss, which makes sense when you consider that it could be acting as either a dopamine agonist or antagonist, depending upon the needs of the patient. It's logical that weight gain/loss would be determined by what action aripiprazole is having in the brain. Link to comment Share on other sites More sharing options...
solstar Posted October 9, 2005 Share Posted October 9, 2005 I take Abilify and have lost a little of my Paxil weight gain while taking it. Link to comment Share on other sites More sharing options...
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