Guest energie Posted July 12, 2010 Share Posted July 12, 2010 ... Link to comment Share on other sites More sharing options...
helenllama Posted July 12, 2010 Share Posted July 12, 2010 A lower dose of remeron will make you tireder. And even if it is making you "happier", you are meant to be at least somewhat functional. From what you are saying you are not functional. Is that right? Link to comment Share on other sites More sharing options...
Velvet Elvis Posted July 12, 2010 Share Posted July 12, 2010 It might help to go up to 45 mgs per day, actually. Does caffeine or any natural stimulants help? Link to comment Share on other sites More sharing options...
Velvet Elvis Posted July 12, 2010 Share Posted July 12, 2010 OK, according to rxlist The mechanism of action of REMERON® (mirtazapine) Tablets, as with other drugs effective in the treatment of major depressive disorder, is unknown. Evidence gathered in preclinical studies suggests that mirtazapine enhances central noradrenergic and serotonergic activity. These studies have shown that mirtazapine acts as an antagonist at central presynaptic α2 adrenergic inhibitory autoreceptors and heteroreceptors, an action that is postulated to result in an increase in central noradrenergic and serotonergic activity. Mirtazapine is a potent antagonist of 5-HT2 and 5-HT3 receptors. Mirtazapine has no significant affinity for the 5-HT1A and 5-HT1B receptors. Mirtazapine is a potent antagonist of histamine (H1) receptors, a property that may explain its prominent sedative effects. Mirtazapine is a moderate peripheral α1 adrenergic antagonist, a property that may explain the occasional orthostatic hypotension reported in association with its use. It's the H1 antagonism that makes you sleepy. It's an antihistamine. It makes you sleepy but on the bright side you won't have any allergy problems while you're on it. That maxes out at a relatively low dose. As you increase the dose the Alpha-1 (noradreniline) antagonism ramps up, making it more peppy. It might be possible to help boost the effect on NA by taking NA precursors such as l-tyrosine which we have for sale in the crazystore: http://astore.amazon.com/crazyboards05-20/detail/B000GFSV28 http://astore.amazon.com/crazyboards05-20/detail/B000ELTDAS L-tyrosine is big with the fitness crowd anyway. I forget why. Search body-building blogs and see what you can find out. Link to comment Share on other sites More sharing options...
rowen Posted July 12, 2010 Share Posted July 12, 2010 I've taken AD's before and didn't have problems with energy levels. Probably 'cause I was manic, but whatever. Most of the newer ones shouldn't be sedating. I agree with VE - 45 mg should help. The noradrenaline kicks into high gear at that point, which should give you the boost you need. L-tyrosine is popular with the fitness crowd because it (drum roll) offsets fatigue. A few members on here take it and have had success. I just started it - I'll let you know how it goes. Link to comment Share on other sites More sharing options...
Velvet Elvis Posted July 12, 2010 Share Posted July 12, 2010 Here's this info page on it from a fitness site: http://www.criticalbench.com/L-Tyrosine-Supplement-Review.htm Link to comment Share on other sites More sharing options...
Velvet Elvis Posted July 13, 2010 Share Posted July 13, 2010 your link doesn't work Link to comment Share on other sites More sharing options...
Velvet Elvis Posted July 13, 2010 Share Posted July 13, 2010 It doesn't say anything about l-tyrosine on there that I can see. Taking B-6 and folic acid along with l-tyrosine will help with its conversion though, and that's got the folic acid. ETA: That review at criticalbench listed some body building compounds that contain it. It might be best to take it as an addon though, I'm not sure. Link to comment Share on other sites More sharing options...
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