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Seroquel tolerance, no longer sedating


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Hi.

I'm taking a very low dose (25mg) at night. At first I started with 12.5 which was sedating as hell then moved up to 25 still sedating only for a few days.

Now it's calming effect actually makes me want to stay awake because of the effect it has. ("supposed" to help me sleep) I expected it

to zombify me or something but seroquel seems to have a unique antidepressant/calming effect. I guess I will have to ask my doc

for a dosage increase but hes out of town for 3 weeks.

Opinions?

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Hi.

I'm taking a very low dose (25mg) at night. At first I started with 12.5 which was sedating as hell then moved up to 25 still sedating only for a few days.

Now it's calming effect actually makes me want to stay awake because of the effect it has. ("supposed" to help me sleep) I expected it

to zombify me or something but seroquel seems to have a unique antidepressant/calming effect. I guess I will have to ask my doc

for a dosage increase but hes out of town for 3 weeks.

Opinions?

I developed a tolerance too. You are still at a very tiny dose. I am at a higher dose now. I love the anti anxiety effect. Too bad your doctor is out of town. If you call his office is there anyone you could talk to about increasing your dose? A doctor covering for him? If you do call I would have a plan, such as asking to increase it to 50 mgs. That is still in the sleeping pill territory.

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Different dose, but I also developed a tolerance. It doesn't stop morning sedation though....

Are you taking it to help you sleep as well as for mood/anxiety? Is it a problem it isn't knocking you out right away anymore?

For me, if I take Seroquel, even if it takes longer, I WILL sleep, whether or not I want to to, eventually. Hopefully you have the same.

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Is it a problem it isn't knocking you out right away anymore?

Yes , I'm also taking it for sleep as well as the mood issues.

At the beginning a mere 12.5mg had that 'I WILL fall sleep' level of sedation. I guess it still helps sleep

but not enough. I'm guessing a dosage increase (from 25 to 50mg) would help this?

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I don't have any experiences with doses at that end but I believe 50mg is a sedating dose and it might help because it would give you the extra oomph, but maybe people who have used it for sleep could weigh in.....

Have you tried taking it earlier to see if it will get you to sleep by bedtime?

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at that dose it's pretty much just an antihistamine so increasing the dose shouldn't change any other pharmacological properties until you get well over 100mgs IIRC

Maybye thats why Benadryl/diphenhydramine helps me?

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