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Considering what's out there, I'm not even sure what would be "2nd best" but really YMMV, but I consider Zyprexa, Seroquel, and Risperdal as the next 3 in lines but I don't know in what order. Mainly it's because they don't cause as much side effects and have been on the market longer to know what to expect with these medications.

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It really varies from individual to individual and what symptoms you're trying to treat. There's also the factor of dose. High dose Abilify will likely be better at treating psychosis than low dose Zyprexa even though high dose Zyprexa is likely going to be more effective than high dose Abilify.

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Best for what? Psychosis? Hallucinations? Unstoppable mania? Rage?

It's really YMMV, but the strongest med I've been on is 20 mg zyprexa. One time I had a big shot of haldol in the er and it was quite calming. I can't take the zyprexa any more due to side effects, so now I take a risperdal/zyprexa combo.

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