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Zoloft killed my sex drive


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I started taking 50mg of Zoloft (generic) about a month ago. I also take Wellbutrin XL 150mg. I've been taking Wellbutrin for a couple years but I was having some bad mood swings with it so my pdoc added the Zoloft.. which killed my sex drive. He then increased my Wellbutrin to 300mg and I had a major panic attack that landed me in the ER after two days of being on that much Wellbutrin. Generic Wellbutrin gave me panic attacks in the past so too much is just too much Wellbutrin for me. 150 is a good dose though, it pulls me out of my depression, gives me energy..just makes me agitated as hell also.

After the major panic attack I stopped taking my meds altogether and was ok for a couple months before I decided to go back on the Wellbutrin and Zoloft. I'm, of course, encountering the same problem.. no sex drive at all. Now honestly, if I was single, I would be okay with this. But I know it's taking a toll on my relationship with my husband. I feel bad that I can't bring myself to have sex with him. I seriously just have no interest at all. I am dead below the waist, essentially. No desire to masturbate or do anything period sexually. It has nothing to do with my attraction to him.. I love him and had plenty of interest before the addition of Zoloft.

I like my med combo because I'm not depressed, not acting crazy, not feeling agitated, I can handle stress MUCH better, and I've even lost a good deal of weight.. I look great and feel great.. I just feel bad when my husband tries to initiate sex and I'm not into it at ALL.

What should I do about this? Are there any other SSRIs that have less sexual side effects than Zoloft? Are there any supplements or therapies or anything I can try to get me back into wanting sex?

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Prozac might be better in that regard or a lower dose of zoloft, as long as its still effective at that dose. There have been some studies showing ginkgo biloba can help, but it takes at least 12 weeks to get in your system and then you don't even know if it will work.

If you live in the U.S. nefazodone might be a good option. Some psychiatrist add nefazodone at a low dose to SSRIs to help relieve sexual side effects or you could take it as an AD on its own.

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Do you have anorgasmia as well? If you don't, just going along with it may help. Sex will still feel good once you get going (lots of lubricant), and you may find yourself getting into it. If you do have anorgasmia...then you'll just find yourself even more frustrated than to begin with.

Just thought I'd throw it out there.

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I've heard Welbutrin can throw a bipolar person into mania. I know it made me anxious sometimes, when I tried it. But the sex was better than normal. Prozac and Celexa both killed my sex drive (and I think they are very similar in formulation). Sex would be fine once we got started, I just never wanted to get started.

Now I'm on trazadone (with lamictal), and sex drive is fine.

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