swanny Posted October 22, 2010 Share Posted October 22, 2010 was on flupenthixol injection every 2 weeks. got up to 80mg. had to stop it coz it was causing akathisia and it was unbrearable. plus i couldnt sleep properly. switched to seroquel xr 400mg about 2 and half weeks ago. my last injection of flupenthixol was on the 29th of septemeber this year. the akathisia has gone down but hasnt completely gone yet. i was reading the leaflet that came with the injection and it said that is could stay in ur system from 3 weeks and up to 3 months! just after different opinions on this. what do you guys think can this injection stay in my system till the end of december? Link to comment Share on other sites More sharing options...
Velvet Elvis Posted October 22, 2010 Share Posted October 22, 2010 If that's what it says in the product documentation, that's probably true. Link to comment Share on other sites More sharing options...
tryp Posted October 22, 2010 Share Posted October 22, 2010 It's definitely plausible. The difference between depot injections and pills is where they wind up in your body. If you take a pill, it goes into your GI tract, and from there it is absorbed directly into your blood. Now, this means it's going to start working, because it can go from your blood to its sites of action. This also means that, since your body is constantly cleaning out your blood, it's going to start getting broken down and eliminated right away too. This is the source of the conventional halflife - how long a dose that you swallow takes to get halfway eliminated from your body. Now, when a doctor gives you a depot injection, it's the same medicine, but it's not going straight into your blood. It's going into your muscle. That's why it's called a DEPOT injection - it creates a little stash of medicine in your muscle that slowly leaks out into your blood over time. Since it leaks out into your blood slowly, it gets eliminated as it leaks...slowly. That's why you only need a shot every couple weeks or whatever it is, but you need to take pills every day. So a depot injection can stay in your system for a while - until it's all leaked out of the muscle. You need a new shot after a couple weeks because not enough is leaking out to treat your symptoms, but that doesn't mean it's all cleared out either. I don't know what the exact numbers are, but it's quite plausible that it might take a good long time for it to fully clear. Tryp Link to comment Share on other sites More sharing options...
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