Anyone know if Corgard or Tenormin are as effective as Inderal?

[NullChamber]

ok maybe not necessarily AS effective, but just effective. i need a drug for akathisia that won't dampen cognitive functioning. i read in the book Answers to Distraction from Halowell and Ratey that these drugs won't have that effect, but they weren't referring to akathisia in the book.

[nibblerd]

Cogentin did not have any effect on my cognition when I took 2mg, so Benzatropine is good.

[notfred]

ok maybe not necessarily AS effective, but just effective. i need a drug for akathisia that won't dampen cognitive functioning. i read in the book Answers to Distraction from Halowell and Ratey that these drugs won't have that effect, but they weren't referring to akathisia in the book.

You need a nonselective betablocker. Those are selective, I think.

nf

[AnneMarie]

Propranolol is a non-selective beta blocker that effectively treats akathesia in some. My pdoc also suggested atenolol (Tenormin). It is a selective beta blocker that tends to be less effective than Propranolol or Inderal. Cogentin is an anticholinergic effective for some people. Then there is good old OTC benedryl which actually works best for me.

[notfred]

The nonselective ones go into the CNS, hence their ability to help with akathesia, but as they are active in the CNS they can cause cognitive issues. Selective beta blockers don't invade the CNS so they are not useful for akathesia.

I have never gotten any cognitive issues with the beta blockers I have used, so it is not a given you will have problems with them.

nf

[NullChamber]

The nonselective ones go into the CNS, hence their ability to help with akathesia, but as they are active in the CNS they can cause cognitive issues. Selective beta blockers don't invade the CNS so they are not useful for akathesia.

I have never gotten any cognitive issues with the beta blockers I have used, so it is not a given you will have problems with them.

nf

hmm, maybe it's the klonopin that's dulling my thinking, then..

[AnneMarie]

The nonselective ones go into the CNS, hence their ability to help with akathesia, but as they are active in the CNS they can cause cognitive issues. Selective beta blockers don't invade the CNS so they are not useful for akathesia.

I have never gotten any cognitive issues with the beta blockers I have used, so it is not a given you will have problems with them.

nf

I have the feeling that my pdoc mispoke about atenolol. My mdoc didn't see that it'd be effective, which makes sense with what you are saying notfred.

I did not have cognitive issues with Propranolol save a little somnolence at high dose. Unfortunately, it did little for my blood pressure and less for akathesia.

[notfred]

I looked it up, only Corgard (nadolol), is non-selective.

nf

[mj1127]

I've taken Corgard for migraine prophylaxis and had no problems with it, though I'm not sure of the dose for migraine relative to that for akathesia. It didn't make me sleepy or stupid, and I think I only stopped taking them because I ran out of refills and couldn't be bothered to go back to the neurologist.

[netsavy006]

There is another medication that is similar to Cogentin that is being mentioned that can help akathisia. It's called Artane (i forget it's generic name but it starts with a T). The dose range for this drug is 1 to 15mg per day so there is lee-way with this medication should you need adjustment for akathisia.

Artane in higher doses I read though can cause some nervousness so you have to be careful with the dosing and usually is dosed 3 times daily from what I remember.

Just a little about what I remember from when I took Artane in the past.