crazycatnapper Posted November 22, 2010 Share Posted November 22, 2010 I suffer from Depression, Anxiety and Narcolepsy. I've tried every AD in the book and in every combination known to man and Pdoc. Parnate is the only med that gives me any relief. It worked fantastic for the first 12 years or so, but has pooped out on me. I went off of it and gave other, new meds a try and other combos a try again. I ended up in the hospital and it was the all time worst depression I've ever been in (I'm 43 and have been battling this since teen years). So I'm back on the Parnate. The life threatening, severe depression is gone, but I'm still depressed. I am also battling the sleepies. I tried Provigil years ago. It made me sick as a dog. While on my Parnate break, I tried the new, improved Nuvigil. It's supposed to be "cleaner" but it make me feel like I had severe morning sickness 24/7. On both meds, I stuck with it for over ten days to see if side effects would diminish, but they did not. The only other medications for Narcolepsy are stimulants and if you read the PI on any of them there is a big NO NO section on taking with Maoi's. To make it even worse for me, I have an ascending aortic aneurysm. When they found it years ago my pdoc pulled me off the parnate because of the "danger". Ended up back on parnate so I could function. He decided I needed some kinda life and it my heart hadn't exploded yet, then it probably wasn't going to. Neither my Pdoc nor my sleep doc would give me a stimulant with my aneurysm. They were afraid to. Surprisingly, no one bothered to mention a thing about mixing it with parnate. About a month ago it was time to see my thoractic surgeon again and have him do Cscan of heart, blah blah. Although my aneurysm is bigger, it's still considered pretty small (too small to operate on even), so I stuck my neck out and asked him about stims. He said the risk was very low and wrote my docs letters saying so. My pdoc put me on 18mg concerta daily. Although it keeps me from falling asleep, it's not a high enough dose for much else. I've been on it a month and am doing just fine. We plan to up my dosage again soon. Just wondering if there is anyone else in the world using both an maoi and a stimulant. There are docs who do it. The research is out there if you look for it, but it's not the norm. One thing that did surprise me is that when filled the concerta CVS didn't freak out on me. Years ago a doc goofed and gave me a med contraindicated with maoi and CVS caught it. Didn't even get a hit this time, and wondering why. Anyway, I am alive and on both with absolutely no problems whatsoever. Link to comment Share on other sites More sharing options...
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