How to take Seroquel IR?

[Pamito]

Hi all,

I have had to increase my Seroquel from 400mgs to 600 mgs. But because of tachycardia and other side effects, I can only take 200mg at a time. So I take 200 at 6pm, 200 at 8pm, and 200 at 10pm. Not too pleasant, as I'm always feeling stoned and hungry all evening. I also take 200 mgs of Solian in the morning, with no side-effects.

Just wondering - if Seroquel's half life is 6 hours, like I have read, should I take some of it in the morning to get a better antipsychotic coverage? Like 400 at night, and 200 in the morning? I just want to function as best I can, and I'm not feeling totally sane at the moment (which is prob why I'm obsessing about taking Seroquel in the morning).

Should I space my Seroquel dosage out during the day for better effectiveness? I am reluctant to because of the sedation, but I want to be as psychosis-free as possible. Am I being silly? And it won't really matter if I take it all at night?

Any advice would be good!

Cheers.

[tryp]

Have you tried the extended release Seroquel? I'm on Seroquel for anxiety and I take the IR at night and then I take some of my dose in XR in the morning. I just wasn't getting the coverage I needed from taking my entire dose in IR.

[themadhatter]

I was having a similiar issue with the IR seroquel. I was feeling stoned and tired all the time like you. My doc split my dose to an xr in the am and IR in the evening for sleep. Maybe try talking to your doc and get on some xr? It really helped me out.

[Pamito]

Thanks for the replies.

The XR Seroquel gave me horrible akathisia. So I have to take the IR.

Would taking it in the morning give me better coverage than taking it all at night? Or will it not make a difference?