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I am so stuck on this, I don't know what to do. I take 200mg Zoloft for depression. And I take 100mg of amitryptilline for migraine prevention. Neither my pdoc nor my neurologist wants to switch meds. I am fairly stable for the first time in awhile, and my migraines are about 5-7 days out of the month.

All good, right? Nope. I have zero interest in sex, and on those occasions I try, it actually hurts a bit. I feel nothing pleasurable during sex.

On further female-related news, I got a mirena IUD last year and haven't had a period since. Course, I'm taking a boatload of risperdal and it made me skip periods last time I was on it.

I really need help. I don't know how much longer my marriage will last through this storm. Any thoughts?

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I know wellbutrin helps some people with this, and maybe remeron, at least theoretically.

If penis/vagina sex isn't doing it for you, maybe investigate other options? Toys? When I've been on SSRI's, I've been able to get off, but it takes a really long time.

The fact that you're having pain makes me think there's something going on either besides, or in addition to, the meds. Your IUD could be weirdly positioned, you could have an ovarian cyst, depending on your age you could have some perimenopause stuff getting started. Probably not anything that's a big deal, but drfinitely worth checking out.

As a purely practical suggestion for the pain, are you guys using lube? If not, give that a try, it could really help a lot. If so, maybe try using more? You never know.

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I know what you are talking about! You are taking 3 potentially libido-killing drugs: Zoloft, Risperdal, and amitryptilline which kill libido pretty much in that order. I don't know what to tell you. I'm finally getting off Paxil, and I will be off an SSRI for the first time in 10 years. I'm hoping to get my libido back because in those 10 years, I've had 0 sex drive. The only advice would be to move to drugs that don't affect the sex drive so much, namely Remeron and Wellbutrin. At least, you might want to talk to your pdoc about replacing the Zoloft. You are on a high dose of Zoloft. I don't know. If you are stable and are feeling good, maybe it's best not to mess with it. Talk to your pdoc.

I don't think that the manufacturers and pdocs realize that when these drugs have sexual side effects, they have the potential for destroying lives and families. People are embarrassed to discuss it, and the problem just gets worse and worse.

ETA: In my experience, adding Wellbutrin to an SSRI does not bring back the libido. However, my Wellbutrin was not added for that purpose.

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