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Pristiq - when did it start working for you


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So far all I'm getting are side effects - icky tummy and some weight loss (probably because of the icky tummy).

I'm only on 50mg right now (don't think I've updated my sig, need to do that) and I see pdoc next Tuesday.

Just wondering if anyone had any good effects early on, or if I'm looking at a full month to 6 weeks.

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First off, Pristiq isn't like other antidepressants. You'll probably stay on 50mgs, as there's actually no gain to going up.

Secondly, for full effect, you should stay on the antidepressant 8-12 weeks. (I've cited STAR*D before, but it's really the best study on how long an antidepressant takes to work out there right now.)

And finally, it started working for me around 4 weeks and I really felt the full effect at 10 weeks or so.

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Yeah. Believe me, I'm not trying to burst your bubble--I think it's possible you'll have SOME improvement far earlier than 8-12 weeks, but for full effect, make sure you wait that 12 weeks before switching meds. (IANAD)

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