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Can you split wellbutrin xl?


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I take wellbutrin. I started at 150 and now take 300. Is 450 the max? My pdoc is thinking of bumping me up to 450 and told me to try combining the 300 and 150 I have left over, and if it goes well he'll write me a script for 450 next time. He told me if I try to split the 300 it's not scored and it will change the effect without the coating intact.

I told him I had enough of the pills to last, but now I realize I'll run out of the 150 before my next appointment. I'm not sure how I feel about the 450. I have more energy, but I feel a little shaky and spacey. I was doing fine on 300, just feeling kinda blah and no energy, but not too bad.

I can go back to 300 when I run out of the 150, but what would happen if I tried splitting the 300?

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The XL has a shell around it that controls the release. If you split it, the shell won't work properly. I believe it will work as immediate release. If that's ok with you, you might as well try?

It may be hard to split it evenly because of the shell -- I don't know -- I take 300 XL but haven't tried to split one.

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Can you call and ask the doctor to call in a prescription for 450? My doc has done that for me before when I've needed more pills between appointments, and it would circumvent the problem.

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Can you call and ask the doctor to call in a prescription for 450? My doc has done that for me before when I've needed more pills between appointments, and it would circumvent the problem.

Thanks. I'll ask what I should do. He might have samples.

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Thanks everyone. I called and he called back. I've never called him before, but I was surprised he had time to talk. He said I shouldn't be shaking, my hands are trembling some. I'm also having trouble sleeping. So he wants me to go back to 300. I have refills on those and they will last until my next appointment.

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