SirHerpDerp Posted July 18, 2011 Share Posted July 18, 2011 I read that at a low dose Seroquel works as mainly an a1 (and h1) antagonist. Does this mean it works similar to Prazosin or Indoramin or something more central acting like Guanethidine or Resperine? Since Seroquel worked so well for some of my symptoms at a low dose, I figure it's the alpha blocking action, and I'm curious if that alpha blocking needs to cross the brain blood barrier or not. Link to comment Share on other sites More sharing options...
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