tommy000 Posted July 18, 2011 Share Posted July 18, 2011 i used to be on regular seroquel 1200mg back when i was 18-20 years old. i found it extremely sedating and i had to take it 3 times a day. 200mg AM. 200mg MIDDAY and 800mg PM. anyway after 2 years i got what i think it to be AKATHISIA. tried cogentin, benzos, beta blockers to try to treat it but didnt do anything for the restless legs. so i had enough and told my doctor to switch me to clozapine even though seroquel was working okay AND the main reason why i asked him to switch me to clozapine was coz of the restlessness which was uncomfortable and annoying. however the restlessness didnt go away with the clozapine even though i was on it for over 2 years. clozapine wasnt treating my schizophrenia aswell as seroquel did. which was weird considering clozapine is meant to be the most powerful while seroquel is to be the weakest dopamine blocker. anyway i got sick of the drooling with clozapine and i was hallucinating quite a bit and couldnt fuction. the reason i stayed on it for soo long was coz ive been on ALL of the atypicals and could only change to something ive already been on. so last october i had enough of not being able to function properly and asked my pdoc to switch me to seroquel XR. after 2 months after the change the restlessness has disappeared. and over the last couple of weeks my anxiety, paranoia and voices have nearly all stopped! it has taken a couple of months to get that full effect. i find XR to be HEAPS more effective than the regular seroquel. im on 1200mg of XR by the way. my main questiion is how is XR more effective than regular for me?? any explanations?? Link to comment Share on other sites More sharing options...
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