hammer Posted July 21, 2011 Share Posted July 21, 2011 I've been doing well on lofepramine (except for the chest pains and tachycardia at 140mg, had to go down to 105mg). Now I'm in the USA relatively long-term and need something that is available here. Unfortunately I will have to go through a GP as I'm still on a waiting list for a pdoc. It looks like desipramine is the closest equivalent, but I'm worried about the cardiac side effects, and this minor detail: Desipramine has been shown to be genotoxic in fruit flies and associated with an increased risk of breast cancer in women Would nortryptiline be a better bet? Or something else entirely? I don't want something that is too strong on serotonin as those tend to make me apathetic and vegetative or just more depressed. Wellbutrin and Lofepramine are the ADs that have worked for me, and I couldn't seem to tolerate the anxiety/agitation on Wellbutrin the second time around. I'm really grateful for any thoughts. Link to comment Share on other sites More sharing options...
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