SashaSue Posted October 16, 2011 Share Posted October 16, 2011 I know that for most people, lower dosages of seroquel are more sedating. I more or less understand why that is the case. But in my long relationship with seroquel, that's never been the case. Never. So, I'm just wondering if I'm the lone weirdo who finds it more sedating at higher dosages? And I'm wondering if there's a secondary mechanism by which it might be sedating, at least for some people, at higher dosages? Link to comment Share on other sites More sharing options...
Velvet Elvis Posted October 16, 2011 Share Posted October 16, 2011 Does trazadone knock you out or other H1 Blockers? Link to comment Share on other sites More sharing options...
mynameisiforgot Posted October 16, 2011 Share Posted October 16, 2011 I'm with you, when I was on 600mg it would sedate me greatly I would end up sleeping 14-18 hours a day. Link to comment Share on other sites More sharing options...
rowan77 Posted October 16, 2011 Share Posted October 16, 2011 The highest dose I took was 700mg and I was like a Zombie. I slept at leasr 14 hours a day and when I was awake I felt dead and was constantly wishing I was in bed asleep. At the dose I take now (400mg) I don't have any of that and only sleep in really late if I don't take my Seroquel early in the night. Before 8pm is my optimum time for taking it, much later than that I'm hungover in the morning. So yeah, I agree with you high doses can certainly knock you out. Link to comment Share on other sites More sharing options...
SashaSue Posted October 16, 2011 Author Share Posted October 16, 2011 Does trazadone knock you out or other H1 Blockers? Not at all. And it elicited a really delightful mixed state. I can take vats of Benadryl with no sedation whatsoever. Link to comment Share on other sites More sharing options...
kitthekitten128 Posted October 16, 2011 Share Posted October 16, 2011 I was extremely tired on it. I didn't tolerate it at all. Unfortunatly I am still trying to find a medicine that wont zombify me. Link to comment Share on other sites More sharing options...
Anna Posted October 16, 2011 Share Posted October 16, 2011 I too get sedated on higher doses of quel, and benadryl does not knock me out, nor traz. Traz just makes me stumbly and WEIRD as fuck, but awake. Not a good med for me. Some people are just like that, I guess. The sedation stays pretty constant at whatever dose, though low doses do work as well, so it's just weird. It's a shame because it would be a good daytime med sometimes except that I literally cannot function on even the ER. Anna Link to comment Share on other sites More sharing options...
enlightened_plutonian Posted October 16, 2011 Share Posted October 16, 2011 I still get sedated on 600mg. I am basically not a morning person at all, and this has become more so since going on Seroquel. I was massively more sedated on 300mg, but I would say that was because I was only on that dose for the first week of taking it rather than lower doses being more sedating. To tell the difference I would have to be on a lower dose for a longer time, but I am not risking the return of my symptoms to check that one out. For me though, the sedation is helpful. Actually I am convinced it plays a part in my symptom reduction, because I proper suck when I am sleep deprived. Link to comment Share on other sites More sharing options...
SashaSue Posted October 16, 2011 Author Share Posted October 16, 2011 For me the sedation doesn't kick in until around 400-600mgs. I'm currently doing a seroquel taper/latuda start up. Since seroquel's the only thing that's even somewhat consistently helped me with sleep over any length of time, I'm not unconcerned about what will happen at lower dosages. Link to comment Share on other sites More sharing options...
Cattitude Posted October 30, 2011 Share Posted October 30, 2011 I found on higher doses of Seroquel (>300mg) I'd be stoned off my ass at first, barely able to find my way to bed. But then I'd develop a tolerance and I'd just get akathesia, which would prevent me from sleeping. Now for sleep I'm on 100mg of Seroquel taken with 7.5mg of Ambien, that seems to do the trick for now. I also take Invega at bedtime, but I don't find it makes a difference to my sleep. I'm only on 3mg for now, so maybe I need to get up to 6 for the full effect. Link to comment Share on other sites More sharing options...
seamonkey Posted October 30, 2011 Share Posted October 30, 2011 Trazodone did nothing for me except give me exploding ass. Benedryl makes me hyper. I used to be able to take 50mgs of seroquel and sleep 8 hours. I'm up to 200 now. I sleep 6-8 hours and not more. I have yet to find a drug that knocks me out longer than 8 hours (except flexeril, which no one will prescribe me any more) Link to comment Share on other sites More sharing options...
Becks Posted October 30, 2011 Share Posted October 30, 2011 Traz, Benedryl, Nyquil, none of them do to me what they are supposed to do. Nyquil actually makes me quite paranoid and when I do fall asleep, I'm constantly jumping and waking up. None of those drugs are very good for me. Traz is at least partly responsible for a manic episode I had back in 2007 when I impulsively decided we need to let our house go into foreclosure instead of fighting for it and move to North Carolina. Ok, back on topic! Serq. IR doesn't sedate me at lower doses either and the Serq XR at 300mg+ knocked me on my ass for days! I had no choice but to switch back to the IR. That said, it does help me stay asleep and I do fall asleep quicker. I like that I can take it early and not zonk out before I'm ready though. Link to comment Share on other sites More sharing options...
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