Aren't Two Antipsychotics Better Than One? (Article)

[netsavy006]

This article comes from "The Last Psychiatrist".

It's an article about using more than 1 antispychotic together.

I'm not sure I agree with the article fully but wanted to share:

http://thelastpsychi...tics_bette.html

(found the article in a google search)

~ Andy

[Damik]

I'm on Geodon and Saphris. I was having breakthrough psychosis while on Geodon alone but haven't had any sense starting the combination. Does that mean that the Geodon isn't working and I'm only seeing the benefit from the Saphris?

[Hooker]

This guy is a total lunatic, different AAP's work on different dopamine and serotonin receptors to different degrees, you can't claim one is equivalent to another just because they are dopamine or serotonin antagonists, they do this in varying forms and to varying degrees.

I would encourage you to post this on crazymeds.us which is specialized on psychiatric medication and watch the article be torn to shreds by people far more knowledgeable than I.

Best.

[Guest Vapourware]

Remember everyone: this is just one article from one person on the internet. As far as I know, it's not even completely clear who The Last Psychiatrist is, except that [i think] they are a forensic psychiatrist of some sort.

He can write some very interesting articles, but please don't base your treatment plan or options based on him. His actual credentials are uncertain and we don't know his research background. He should be viewed as a random on the internet and therefore with some scepticism.

[Blart752]

I agree with him, two antipsychs is overkill IMO. even for the worst, just switch to something stronger. There was an article that i posted awhiles back about two antipsychs, and i cant seem to find it, it came to the same conclusion that isn't necessarily better or something like that, it was a real article.

[lysergia]

I would encourage you to post this on crazymeds.us which is specialized on psychiatric medication and watch the article be torn to shreds by people far more knowledgeable than I.

this is an excellent idea. if anyone would like to do so, i'd love to watch.

i'm tempted to ask for a roll call of everyone here at CB who is taking two AAPs.

i'm one of them.

my pdoc is the head of the mood disorders unit for the city where i live. she is not stupid, ignorant, uninformed, uncaring, or naive. she has no problem prescribing more than one AAP if THAT IS WHAT WORKS without intolerable side effects.

it isn't necessary for everyone, but for some, it's the difference between choosing life over death.

i'm probably one of those, too.

"something stronger" does not exist. it's not like if your antipsychotic doesn't work well enough, you bump up to a "stronger" one. they aren't pain meds. there isn't a continuum. there's only what works for the individual.

[muriel]

TLP is pretty well respected in the field and for his rational way of looking at psychiatry.

This is an article I read years ago and one that a practitioner I know was very impressed by knowing how AAPs work clinically. The article makes a lot of sense.

I wouldn't dismiss this one out of hand, and I wouldn't necessarily take the word of those at Crazymeds over this article. The people at Crazymeds don't know more than doctors and suffer their own myopic viewpoints much to their own detriment more than anything else, IMO. People at Crazymeds aren't doctors, and don't see the clinical effects of these drugs in multiple people over many years. I'm not saying TLP is right, I'm just saying that the people on Crazymeds, armed with journals or not, are no more knowledgeable than we are because they simply don't have clinical experience or training. I would certainly give TLP the benefit of the doubt in general over CM knowing his history.

It doesn't mean 2 AAPs aren't the right choice for some people, though. No one is right 100% of the time. I just don't think the people at CM have any more knowledge or insight than many of the people here. We are all patients, not clinicians.

If you read to the end of the article, keep in mind that he was ONLY talking about psychotic and manic symptoms. This is the last line from the article:

"Now, these other receptors might be relevant for other effects (reducing anxiety, antidepression, etc) but let's try to focus on the specific problem and not get all Andrew Weil here."

[jt07]

You have to go with what works for you regardless of what anybody says on the internet. If you and your doctor find a treatment regime that works, stick with it. All that's important is whether it helps you or not.

[Velvet Elvis]

TLP is pretty well respected in the field and for his rational way of looking at psychiatry.

This is an article I read years ago and one that a practitioner I know was very impressed by knowing how AAPs work clinically. The article makes a lot of sense.

I wouldn't dismiss this one out of hand, and I wouldn't necessarily take the word of those at Crazymeds over this article. The people at Crazymeds don't know more than doctors and suffer their own myopic viewpoints much to their own detriment more than anything else, IMO. People at Crazymeds aren't doctors, and don't see the clinical effects of these drugs in multiple people over many years. I'm not saying TLP is right, I'm just saying that the people on Crazymeds, armed with journals or not, are no more knowledgeable than we are because they simply don't have clinical experience or training. I would certainly give TLP the benefit of the doubt in general over CM knowing his history.

It doesn't mean 2 AAPs aren't the right choice for some people, though. No one is right 100% of the time. I just don't think the people at CM have any more knowledge or insight than many of the people here. We are all patients, not clinicians.

If you read to the end of the article, keep in mind that he was ONLY talking about psychotic and manic symptoms. This is the last line from the article:

"Now, these other receptors might be relevant for other effects (reducing anxiety, antidepression, etc) but let's try to focus on the specific problem and not get all Andrew Weil here."

+1

[muriel]

TLP is pretty well respected in the field and for his rational way of looking at psychiatry.

This is an article I read years ago and one that a practitioner I know was very impressed by knowing how AAPs work clinically. The article makes a lot of sense.

I wouldn't dismiss this one out of hand, and I wouldn't necessarily take the word of those at Crazymeds over this article. The people at Crazymeds don't know more than doctors and suffer their own myopic viewpoints much to their own detriment more than anything else, IMO. People at Crazymeds aren't doctors, and don't see the clinical effects of these drugs in multiple people over many years. I'm not saying TLP is right, I'm just saying that the people on Crazymeds, armed with journals or not, are no more knowledgeable than we are because they simply don't have clinical experience or training. I would certainly give TLP the benefit of the doubt in general over CM knowing his history.

It doesn't mean 2 AAPs aren't the right choice for some people, though. No one is right 100% of the time. I just don't think the people at CM have any more knowledge or insight than many of the people here. We are all patients, not clinicians.

If you read to the end of the article, keep in mind that he was ONLY talking about psychotic and manic symptoms. This is the last line from the article:

"Now, these other receptors might be relevant for other effects (reducing anxiety, antidepression, etc) but let's try to focus on the specific problem and not get all Andrew Weil here."

+1

Hey, didn't we disable that function on purpose here? Plus, I want "insightful" too. No, maybe "informative" is better.