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What is the reason serequel causes weight gain?

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What causes the weight gain from serequel? Is it the increase in appetite? Does it change your metabolism.

What causes the increase in cholesterol/lipids? Does the increase in appetite occur at low doses such as 300mg or is it more prevalent at higher doses? Answers will be greatly appreciated.


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AAPs have two mechanisms of action.... they can change your metabolism and they can also make you hungry. As far as I know, it may be changes in glucose metabolism that both cause the increase in appetite, and ensure that whatever you eat will be more likely to make you gain. I believe that is why metformin is helpful in some AAP weight gain.

I'm not sure what causes the cholesterol changes, to be honest.

I had appetite changes and weight increase on 300 m.g. of seroquel, and I don't notice any real changes with dose changes.

Another way to ensure that you don't gain too much is to watch your diet carefully..... I was able to lose 45 lbs on Seroquel and depakote by reducing my carbohydrate intake. As well as exercise. This did not improve my chol. levels, however.


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