Trix Posted February 24, 2012 Share Posted February 24, 2012 I have the choice between Zyprexa 5mg or Seroquel 100mg. Which one is better or stronger? (I'm also on clozaril 800mg. It's just an add-on.) Link to comment Share on other sites More sharing options...
lindamine Posted February 24, 2012 Share Posted February 24, 2012 I would say to try one the first night and the other, the next. I found Seroquel to be extremely sedating for me-well into the next day it lasted. Good luck, and remember, we all respond differently. Link to comment Share on other sites More sharing options...
Eden Posted February 25, 2012 Share Posted February 25, 2012 For me seroquel was very sedating but it was also uncomfortable, I couldn't sleep on it and found it didn't clear up my psychosis. Zyprexa cleared up my psychosis, it let me sleep and it wasn't uncomfortable, but I gained a lot of weight on it. In seroquels defense thats not a very common opinion, a lot of people here really like it. Personally I would try seroquel first, if it works for you stay on it, zyprexa is an excellent drug IMO, but it isn't a very good drug to take long term. Link to comment Share on other sites More sharing options...
koa Posted February 25, 2012 Share Posted February 25, 2012 I have never been on Seroquel, but I really hated being on Zyprexa because I would sleep 12+ hours a day (which might be a good thing if you are having trouble sleeping) and I gained about 50 pounds. Link to comment Share on other sites More sharing options...
Velvet Elvis Posted February 25, 2012 Share Posted February 25, 2012 5mgs zyprexa is a lot stronger than 100mgs seroquel. 100 mgs seroquel isn't even in the range where it's effective for psychosis. Link to comment Share on other sites More sharing options...
larkspur Posted February 25, 2012 Share Posted February 25, 2012 I love Zyprexa. I took it for a week to come out of a bad hypomanic place and it is a wonderful drug. After a few days it didn't make me drowsy at all. I took 10mg during the day. It can cause diabetes and weight gain though. I'm on Seroquel XR 300mg now, and I don't like it near as well as the Zyprexa. Link to comment Share on other sites More sharing options...
Trix Posted February 25, 2012 Author Share Posted February 25, 2012 I'll go with the Zyprexa. Seroquel has worse side effects I think. Link to comment Share on other sites More sharing options...
red_dirt_angel Posted February 25, 2012 Share Posted February 25, 2012 I was taking Seroquel 50mg because I have trouble getting to sleep (racing thoughts, and a fear of encountering nightmares). I went and saw a GP yesterday, on advice from my tdoc who wanted me to start again on an SSRI (I used to take 100mg Pristiq, but it made me really agitated sometimes...). The GP ignored that request, saying that all I need is a good nights sleep (hahaha...) and things will start getting better (hahaha). When I told him that I was starting to build a tolerance to the seroquel, he wrote me a script for Zyprexa 10mg. I took one last night around 10pm, and didn't wake up again til 4pm the next afternoon.... I've read a lot about the weight gain on this aswell, and am thinking that I might try and find a GP that will actually listen to what I have to say, because this GP yesterday seemed a bit too happy to prescribe this - right after I said that I'm scared of drugs that might cause weight gain... Link to comment Share on other sites More sharing options...
enlightened_plutonian Posted February 25, 2012 Share Posted February 25, 2012 I like Seroquel, but I take 600mg. At 100mg it is only really a sedative. I would say that Seroquel took some time to get used to it, but for me the sedation is now just enough to stop my insomnia. Other than that, which is helpful actually, I don't get any other side effects. I have never tried Zyprexa though. But if VE said that the dosage would be better then that may be a good option to go for. Different meds affect people differently, so the only way you would know which is best for you is to try both and see which you prefer. Look at what are you taking it for, and what effects you are looking for. Link to comment Share on other sites More sharing options...
g8orgirl Posted February 26, 2012 Share Posted February 26, 2012 I'm currently on Seroquel but I did take Zyprexa for a few months. I found the Zyprexa to be more sedating than the Seroquel and I also gained about 60 lbs on it in less than 6 months. But, everyone's experience is different, I found that the Seroquel was better at controlling my psychotic symptoms and that's why I'm still on it. Link to comment Share on other sites More sharing options...
Pamito Posted February 27, 2012 Share Posted February 27, 2012 I find seroquel is a better anti-psychotic, PERSONALLY. Zyprexa didn't do anything for me even at 30mg. BUT everyone responds differently to different meds, as you can see in this thread. I believe 5mg of Zyprexa could cause some weight gain. It's up to you to try them both. Hope that helps. Link to comment Share on other sites More sharing options...
Velvet Elvis Posted February 27, 2012 Share Posted February 27, 2012 If clozaril doesn't cause weight gain, it's unlikely that Zyprexa would. Link to comment Share on other sites More sharing options...
larkspur Posted February 27, 2012 Share Posted February 27, 2012 Zyprexa has a generic, so it may cost you less. Link to comment Share on other sites More sharing options...
chimpmaster Posted February 28, 2012 Share Posted February 28, 2012 Out of interest, why just the two options? I would have thought that if you are already on a high dose of cloz (which you are) something like abilify or geodon would possibly be worth considering as well.... Link to comment Share on other sites More sharing options...
ManWitPlan Posted February 28, 2012 Share Posted February 28, 2012 Isn't seroquel/zyprexa contraindicated with clozaril? http://www.drugs.com/interactions-check.php?drug_list=709-364,1979-1274 Heck it seems like it is with any antipsychotic. But I guess they do it in cases where its necessary. Zyprexa is definitely stronger at 5 mg than seroquel 100. Zyprexa at 5 mg gives you antipsychotic action where as seroquel 100 doesn't. Zyprexa when I took it made me feel pretty good but the seroquel atleast initially made me uncomfortable when trying to sleep. Link to comment Share on other sites More sharing options...
Trix Posted February 28, 2012 Author Share Posted February 28, 2012 My pdoc said I would benefit from an extra anti-psychotic and gave me the choice of the two because I had bad side effects from others. I've been just taking the zyprexa and haven't tried the Seroquel and I like it so far. Link to comment Share on other sites More sharing options...
saoirse Posted February 28, 2012 Share Posted February 28, 2012 If you like the zyprexa then I would stick with it. Both were sedating to me, but zyprexa caused a ton of weight gain in just two months. Link to comment Share on other sites More sharing options...
juan Posted May 11, 2017 Share Posted May 11, 2017 Hello there: Seroquel for me it has a milder effect that Zyprexa. It does make you sleepier, during the day, Zyprexa has a potent effect on sleep, but for 10 hours aprox. Link to comment Share on other sites More sharing options...
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