Electrawoman Posted March 1, 2012 Share Posted March 1, 2012 Following a 30-day Cymbalta trial for anxiety (not very severe), I started taking Pristiq 50mg 9 days ago. I have had a few mild side effects that seem to be improving so I am thinking that this one may be a keeper. However, I also notice that the drug seems to wear off about 5 or 6 hours prior to my next dose. Does anyone else take Pristiq twice a day? What are your experiences? Also, For those of you cataloging side effects, here are mine. Some of these may be related to the Cymbalta withdrawal because I really did not wean down from cymbalta 60 for more than a few days before starting Pristiq. Symptoms started out light, peaked, then started to dissipate: Days 1-5 Vivid Dreams Light Sleep Teeth Clenching Lightheaded Mild Headache Insomnia Day 5 (all of the previous symptoms PLUS...) Overreacting Major anxiety obsessive thoughts self mutilation urges (NEVER experienced that before) Heart Racing Insomnia for 48 hours Day 6 All of the above, but lessening in severity Day 7 Light Headache Tight Muscles Moody (irritable, then ecstatic) teeth Clenching Light Sleep Lightheaded Day 8 Happy! Energetic! sore muscles Day 9 Sore muscles slightly irritable but generally happy teeth clenching Link to comment Share on other sites More sharing options...
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