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Could a double dose cause serotonin syndrome?


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I took my Zoloft twice by mistake.  I am absorbed in my studies at the moment and tend to be a little absent minded when it comes to taking my meds (though I always take them), and I hastily assumed, last night, that I had forgotten to take my meds in the morning.  So, I took 200mg on top of the 200mg that I had in fact taken in the morning.  I have done this before by accident but did not experience any problems.

When I was in a relaxed state trying to get to sleep I noticed that my body was twitching involuntarily.  I having rapid muscle contractions.  They were mild, but they were there.  Another symptom that I noticed was abnormal movement of my feet.  My reflexes were also in over drive.  My body would react to a twitch by rapidly contracting the muscle in the area affected.

I ask because I am currently of an AP at the moment (Seroquel), and this can cause movement disorders as well.

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I took my Zoloft twice by mistake.  I am absorbed in my studies at the moment and tend to be a little absent minded when it comes to taking my meds (though I always take them), and I hastily assumed, last night, that I had forgotten to take my meds in the morning.  So, I took 200mg on top of the 200mg that I had in fact taken in the morning.  I have done this before by accident but did not experience any problems.

When I was in a relaxed state trying to get to sleep I noticed that my body was twitching involuntarily.  I having rapid muscle contractions.  They were mild, but they were there.  Another symptom that I noticed was abnormal movement of my feet.  My reflexes were also in over drive.  My body would react to a twitch by rapidly contracting the muscle in the area affected.

I ask because I am currently of an AP at the moment (Seroquel), and this can cause movement disorders as well.

First (and always a good idea when there seem to be new side effects) call your pdoc. The fact that the twitching is in your feet appears to be significant.

2) Aidsmeds Rxcheck doesn't list any seroquel-zoloft interactions (which doesn't mean there aren't any). Just a warning for each about drinking grapefruit juice.

https://www.aidsmeds.com/cmm/DrugsNewContent.asp

3) I've had the leg twitching (RLS?) but clearly caused by seroquel at pretty low doses (150 mg); which was really too bad, because it was the best "falling asleep" Rx ever. Had to discontinue it, but three months later at lower doses (50-100 mg) I resumed it and it was OK, just not as effective as before. Crazymeds doesn't list twitching of this sort as a side effect of zoloft.

Hope this helps, but let me say one thing again:

Call your pdoc! It probably is not serotonin syndrome imho, but on the other hand serotonin syndrome is nothing to mess around with.

tom

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I took my Zoloft twice by mistake.  I am absorbed in my studies at the moment and tend to be a little absent minded when it comes to taking my meds (though I always take them), and I hastily assumed, last night, that I had forgotten to take my meds in the morning.  So, I took 200mg on top of the 200mg that I had in fact taken in the morning.  I have done this before by accident but did not experience any problems.

When I was in a relaxed state trying to get to sleep I noticed that my body was twitching involuntarily.  I having rapid muscle contractions.  They were mild, but they were there.  Another symptom that I noticed was abnormal movement of my feet.  My reflexes were also in over drive.  My body would react to a twitch by rapidly contracting the muscle in the area affected.

I ask because I am currently of an AP at the moment (Seroquel), and this can cause movement disorders as well.

First (and always a good idea when there seem to be new side effects) call your pdoc. The fact that the twitching is in your feet appears to be significant.

2) Aidsmeds Rxcheck doesn't list any seroquel-zoloft interactions (which doesn't mean there aren't any). Just a warning for each about drinking grapefruit juice.

https://www.aidsmeds.com/cmm/DrugsNewContent.asp

3) I've had the leg twitching (RLS?) but clearly caused by seroquel at pretty low doses (150 mg); which was really too bad, because it was the best "falling asleep" Rx ever. Had to discontinue it, but three months later at lower doses (50-100 mg) I resumed it and it was OK, just not as effective as before. Crazymeds doesn't list twitching of this sort as a side effect of zoloft.

Hope this helps, but let me say one thing again:

Call your pdoc! It probably is not serotonin syndrome imho, but on the other hand serotonin syndrome is nothing to mess around with.

tom

<{POST_SNAPBACK}>

Luckily I had an appointment with my General doc the nest day anyhow.

He said that there was no problem if these symptoms did not persist.

They did not.

I would have called my psyc, but he is on holiday.

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