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Adderall + Effexor = a calmer me O.o ?


semtex

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I had been on 300 mg Effexor supplemented with Gabatril for a while. Those 8 mg of Gabatril were supposed to be treating anxiety/insomnia but were doing fuck all and maybe were even making my depression/mood swings WORSE.

So last week my pdoc prescibes Adderall at 20 mg and DECREASES the Effexor to 175 mg. After I told hiim in a nutshell what I had been discussing w/ my therapist he thinks that while the Effexor may be helping my depression it seems I may have a touch of ADD so the Adderall would help that.

I'm just wondering if anyone else has been on this kind of combo & what to expect, anyone?

What's REALLY blown my mind is this, since starting the Adderall, I've been:

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good deal Bella!

there may be some come down after your dose wears off, but as others on this CNS topic have stated . . that come down effect wears off a bit after time and isnt as harsh.  That's been my experience, i dont have really anykind of comedown other than some increased OCD and a bit of anxiety for a half hr or so.  Nothing that exercise doesnt chase out of me, and then i feel pretty damn refreshed after working out.  happy pumpkins  ;)

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jonathan, how much are you on now?  i remember you took 30 in the am and 10 in the afternoon, is that right?  have you tried sr?

it's still very early but i'm thinking adderall is the right drug for me, now i just have to find the ideal dosage!! 

didn't sleep well last night - woke up feeling fine after 6 hrs of sleep, but forced myself to sleep another hour + ...  just wondering how to combat that.

k, enough out of me re: adderall.... for now  ;)

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bella

i'm on 15 mgs of XR at around 8 a.m., and then about 1-2 hrs later i take 10 mgs of XR . . for some reason this takes the wired effect out of just taking a 25 mg xr capsule.....at taking a 20 mg XR capsule i still felt wired, but taking two doses i can at least work out the range of being balanced and awake, thus and not as wired.

i didnt sleep a whole lot at first either....and i still dont (5-6 hrs) during the week . . i wake up seemingly at least 1 time 3-4 hrs after i've been asleep . . (this is mainly to go to the bathroom, and eat...the Lex makes me a bit hungry when i wake up, and my stomach feels pretty empty so i just get a bowl of cereal ..at the very least its healthy cereal Kashi), though i make sure i get 8-10 hrs of sleep if not more on Saturday and Sunday...if i dont get a lot of sleep, as others have said, my OCD gets a little more intense.  the whole not getting a lot of sleep is dictated by my job throughout the week, i go to work, and then get home around 5 pm and have stuff to do until 12 to 1 in the morning. 

the sleep issue is an issue for me, cause i've seemingly never been able to get enough sleep . . sleep apnea/narcoleptic issues . . . i could sleep 10-12 hrs and feel only a bit refreshed . . . so 5-6 hrs for me is seemingly like 2-3 hrs for someone without issues . . . i'm checking out a sleep doc come first week of November . . should be interesting.

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it's still very early but i'm thinking adderall is the right drug for me, now i just have to find the ideal dosage!! 

didn't sleep well last night - woke up feeling fine after 6 hrs of sleep, but forced myself to sleep another hour + ...  just wondering how to combat that.

k, enough out of me re: adderall.... for now  ;)

<{POST_SNAPBACK}>

Are you on the extended release or no? XR is supposed to be "smoother"

I take mine (the Adderall XR) as early as possible. I actually felt kinda tired at 12 AM last night!

That is very shocking bcause I never g2 bed that early! (lol more like 1:30 am or 2 & then I have to get up at 7:30)

Ok but THEN I woke up this morning at 4 AM! I worked on stuff for a couple of hours and then went back to sleep at 6 which was a big mistake because then I woke up late. I should've just stayed up! I mean, I felt awake!

I don't think it was the Adderall. It could have been the Effexor or just my shitty-ass inability in general to sleep more than 4 hours at a time.

OH WELL.

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johnathan, that's interesting about spacing out two xrs - i have a feeling that is the road i am headed for.  i'm sensitive on both ends of the spectrum - sedation *and* anxiety. 

i need at least 8 hrs of sleep to feel good.  i get by on 7 a lot, but less than that and my anxiety gets really bad.  i would imagine much like your ocd.

semtex i take xr, as well.  i bet it is the adderall keeping you up - maybe combined w/ the effexor?  i take zoloft too, and when i first started the zoloft it kept me from sleeping.  about 4 days later it made me sedated, now it seems to be pretty neutral, but i wonder if zoloft + adderall is what is perhaps keeping me up again, and might be the same for you ?

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semtex i take xr, as well.  i bet it is the adderall keeping you up - maybe combined w/ the effexor?  i take zoloft too, and when i first started the zoloft it kept me from sleeping.  about 4 days later it made me sedated, now it seems to be pretty neutral, but i wonder if zoloft + adderall is what is perhaps keeping me up again, and might be the same for you ?

<{POST_SNAPBACK}>

Actually now I'm sleeping much better now than I have in YEARS. O.o

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  • 2 months later...

I'm now taking Adderall as an adjunct to my Effexor XR 150mg, to try to crack my treatment-resistant depression.  Pdoc started me at 10mg which had no noticeable effect, then increased it to 10mg twide a day.  I felt some improvement, in mood and an almost complete drop in suicidal ideation, and where the Effexor had been putting me to sleep at work before, that heavy drowsiness was gone.  But after about a week, the effects seemed to dissipate.  The pdoc upped my dosage to my current 20mg twice a day.  Once we got to the current dosage, things improved drastically for about three weeks - I actually felt somewhat normal for the first time in forever, although I found it difficult to get to sleep before 2am.  Now the positive seems to be tapering down again.  The gloom is creeping in, the suicidal thoughts have peeked their foul heads around the corner, and my head wants to hit the desk every day at almost precisely 4pm.  Has anyone had any experience with the poop-out rate for Adderall?  Especially for depression?  I noticed somewhere else on this board that someone reported that Adderall's antidepressant effect was transitory.  Has anyone experienced this?  And lastly, what are the effects of long-term use?

Cerberus

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i've had a bit of come-down depression after my dose wears off (i take Adderall XR at 25 mgs once a day)........taking a bit of Lexapro has helped take the anxiety out of the scene, but the depression has been still there....though recently i've been taking Gabitril (an anti-convulsant) and it definitely has helped with the come-down, i dont even notice the come-down effect anymore........though not every med is perfect and i've still had issues with the Gabitril (it can make me a bit stupid for the next 8 hrs after i take it).....

i'd watch out for the high blood pressure with taking both the Adderall and the Effexor........Inderal is a good med for blood pressure and social anxiety as well.......though taking an anti-convulsant may be a pretty good choice

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