MoparGuy1991 Posted October 25, 2005 Share Posted October 25, 2005 I'm currently on 400mg Lamictal and 250mg Topamax for Bipolar-NOS. They are working fine as mood stabilizers. I'm pretty stable, and I have no more Mixed States. However, I've still been having problems with depression and some obsessive/compulsiveness. At baseline mood, I'm sad/tearful a lot, I feel like a failure, I often have negative outlook, and I don't have much confidence in myself. When I hear a song that's supposed to be uplifting, I feel sad from it instead. Also, I feel numb sometimes to positive/happy emotions but usually not to mournful ones. So, at my appt. today, my doctor added 5mg of Lexapro. He told me not to escalate right to 10mg because my system needed to adjust to it. I'm taking it for the 3rd time. I took Lexapro two other times. 1st Time- 20mg I was put on it due to severe Mixed State depressions. Depakote (my mood stabilizer at the time) already hadn't been working at all before Lexapro was prescribed. So, Lexapro was the only drug really having an effect over few months I took it. It worked very beautifully. It kicked in after 3 weeks. No manic switching or destabilzation despite not having a working mood stabilizer. I went off Lexapro cold turkey myself, and the severe Mixed States came back with a vengeance then....!!!! 2nd Time- 20mg First few weeks I was on it, I started to get same benefits I got first time. However, I had a moderate depression episode before the drug took full effect, and we saw the doctor. I wasn't on a mood stabilizer yet. He added Geodon and started me on Topamax for mood stabilizer (which had slow titration). Well, 5 days after having Geodon added to Lexapro, I started to become Manic as Hell and stayed in that phase for 6 weeks 'til Geodon was stopped [temporarily] due to a manic attack. Topamax was upped to 200mg then. Later, Lexapro was dropped on this 2nd trial due to the Manic Attacks from the Geodon and Lexapro interaction. Lexapro ALONE, though, never caused mood switching really. Last time I took Lexapro was over 1 1/2 years ago. Does anyone have experiences with taking only 5mg of Lexapro? How does it work for you? And since I take Lamictal, does this mean that I would require a lower dose of Lexapro than I would have before otherwise? I've seen studies where they combined Lamictal with SSRI's for TRD and found that they synergized well. Link to comment Share on other sites More sharing options...
This topic is now archived and is closed to further replies.