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I have never tried Seroquel and I don´t know any test that evaluates histamine receptors. However, when my pdoc decreased my cymbalta´s (antidepressant) dosage, I started having breathing problems I had never experienced before. I didn´t know what was happening so I went to my GP who told me I was having an allergic reaction and prescribed Zyrtec.

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I've found nothing to imply that it would. Are you worried it might happen or worried it has happened?

I'm worried that it has happend. I took Seroquel for about 6 month and when I went off them I experienced bad itching all over my body and scalp + very dry skin on my face. I still have allergy symptoms in eyes, nose and the bodyitching comes and goes. I've had allergytests but I'm not allergic. It's been more than two years since I stopped taking the pills and I havn't taken any other medicin since. But the symptoms are still there. Kind of makes me wonder...

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I've found nothing to imply that it would. Are you worried it might happen or worried it has happened?

I'm worried that it has happend. I took Seroquel for about 6 month and when I went off them I experienced bad itching all over my body and scalp + very dry skin on my face. I still have allergy symptoms in eyes, nose and the bodyitching comes and goes. I've had allergytests but I'm not allergic. It's been more than two years since I stopped taking the pills and I havn't taken any other medicin since. But the symptoms are still there. Kind of makes me wonder...

Cherry Girl: besides of what I described before, I also experience itching while reducing dosage of cymbalta. It went away when my dose was increased. I thought that the itching was caused by poor circulation and sugar problems, but now that you mention histamine, I don´t know if it might be related to that.

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  • 1 month later...

I have taken Zyprexa for 6 years. For the past year, I´ve noticed I have new allergies and symptoms I didn´t have before. Like sneezing, runny nose and a weird symptom in the nose that won´t go away. I read that zyprexa works on histamine receptors. Could it be that my receptors turned more sensitive/sensible to histamine???. What are the long term effects of zyprexa on histamine receptors?

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