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I'm sure there are plenty of people on here who have been on Effexor with both good and bad stories, but does anyone have a rough idea about how long it takes to "get used" to a new dose? I went up to 300mg recently and I'm just wondering because I feel like I have more nervous energy. Thanks!

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Usually, for me, it takes a week or two to get used to a new dose of an AD. Sometimes sooner but I try to give it two weeks. If it gets unbearable, call your pdoc.

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