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problems coming off clozaril


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my sleep was so bad i got maybe 4 hours. i had all this nervous energy and my thoughts were kind of racing in the beginning.i'm not feeling manic or was feeling manic but that was just hell. i hope it goes away. i called my case worker she's gonna call me back once my doc gets in but i was wondering if this was common with anyone else getting off cloz? i read that rebound mania is common. i am on latuda now but i still slept horribly. on the flip side i can get up at 10am now, 2 hours earlier then when i was on cloz on the higher doses.

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Yes is very common almost expected. See clozaril blocks a huge amount of the h1 histamine receptor. Latuda doesn't touch that receptor at all. So insomnia and anxiety is the result when you go from a strong histamine blocker to no blockade of histamine. So this is completely normal and I wouldn't worry.

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