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There seems to be two kinds of adjustment to drugs....One is permanent that your body remembers and the other is temporary that you go through again every time you start a drug again. The second and third time I took risperidone I never experienced side effects like restlessness, increased prolactin, hunger etc. The second time on risperidone i went like1mg 1-4, 2mg 4-8, 3mg 8-12 (days) thats when I started feeling that with every day my body adjusted to risperidone more and more. I then went up to 4mg and stayed there for about 3 weeks, feeling terrible and suicidal the whole time. I then went ONE mg lower to 3mg and actually felt really good and had reinstitated interest in everything. I suppose this is simply hyperadjustment? back then I went from 3mg to 2mg and felt no difference, but going from 2mg to 1mg the good feeling stopped. I have been on 2mg risperidone for 4 weeks now and I feel BAD with 2mg, still bad with 1mg, I am now trying 0.5 + 0.5 a day. How long can it take for your body to adjust, or maybe risperidone is such a strong drug that my body will not adjust at all unless subjected to high doses (in that maybe your body feels it takes alot of resources or whatnot to the adjustment process?)? Maybe all I need is 0.5mg a day and I will feel good? I guess Ill find out today. I have also been on seroquel the whole time. its still IR and the dosage is same. Its the seroquel that keeps me stable, not risperidone. I dont need risperidone in any dose at all, all i want it is for the good feeling. My pdoc said that the necessary dose lessens with time, but it doesnt fit into my head how after having been on the drug (and off) more time you are less adjusted?

Sorry for the rant. Should never have gone to abilify/amisulpride in the meanwhile.

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Every medication will cause different reactions. Have you given the meds a long enough chance to work to see if the side effects go away? It seems like you are constantly changing doses, which IMO would constantly cause symptoms/reactions. You need to keep it at one level to see if the side effects go away.

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I havent. I went to 2mg and stayed there for 4 weeks, the better it started working the worse I felt....Its prolly the effect not a side effect. I cant compare the first time because coming from 7 years of prodromal/psychosis I was well numbed to any bad feeling. And the second time it was obviously clouded by the high dose.

I took 0.5mg the morning and got bad withdrawals (depression). So therefore I concluded that any dose that has any much of an effect will make me feel bad which proves its from the effect. I decided I will try upping my dose to 3mg then 4mg for some days, I should feel when it starts adjusting.

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I'm wondering why you're changing your dosage every few days. You're going to give yourself med whiplash. It really isn't a good idea. Is your pdoc okay with this? You're not giving yourself enough time to adjust to a dose before you change it again. It sounds like from what you said that 2mg isn't enough and 4mg is too much. If your pdoc is okay with it, why don't you try 3mg for several week. Like a minimum of 6 weeks and see what happens.

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I think you are making WAY too many changes to your risperdal. I take 6 mg of it and it took me a year to slowly work up to that dose... And most of that first year was going from 0-3mg. I didn't go to 4 then 6 until I started having hallucinations. But those dosage increases were slow and done by my pdoc.

Does your pdoc know you are doing this much medication changing? If not, you need to call them ASAP and fess up. If they give you "leeway" to adjust your risperdal, I'd still give them a call and let them know just how much and how fast you've been changing things.

You will probably feel better once you get on a more standard schedule. But you'll need to give it a week or two.

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