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I'm on both of them plus some other stuff right now.

That small a dose of seroquel is really not much more than a sleep aide.  It's helped my anxiety and OCD quite a bit, but not until I got into the 100mg range.  Once you get into higher doses (300mgs, give or take) it's less sedating, by the way. 

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Saw my doc yesterday, he gave me wellbutrin [xl- 150mg in the mornings] in adition to the seroquel [50mg] and lexapro [20mg] that i already take. I'm waiting untill tomorrow morning to start the Wellbutrin incase it makes me sick or something.

I'll let you know my experiances if there's anything interesting to report.

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Eventually my body got adjusted to the dose of Seroquel and it made me less and less sleepy.  But those first few nights...woo!  I was really sleepy.  Also, more seroquel, even up to 400 mg made me more sleepy but as my nighttime dose got higher I was able to tolerate a 25 mg booster in the afternoon.

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