deeschmee Posted May 15, 2013 Share Posted May 15, 2013 Over the years I've taken Benadryl (not for antidepressant) Amitriptyline Topamax and Rozerem ALL which have made me hyper as hell!!! I literally was awake ALL night with Benadryl, amitriptyline and rozerem. Ambien only gives me about 4-5 hours of undisturbed sleep. Can anyone relate? Do these meds have something in common that may cause someone with bipolar to be manic? My p-doc is confused especially about the Topamax. Maybe its my chemical makeup that reacts strangely to these meds. Is there any articles regarding this thought? I'm headed to a sleep study this Sunday so maybe this will show something. Any suggestions? Not sure if I posted this in the right section....sorry! Link to comment Share on other sites More sharing options...
Parapluie Posted May 16, 2013 Share Posted May 16, 2013 Benadryl and all cough syrups containing pseudoephedrine make me hypomanic for days. Normal Benadryl doesn't contain pseudoephedrine, but one variety of it does. Each 5 mL of Benadryl Chesty Cough & Nasal Congestion contains 100 mg of guaiphenesin (an expectorant) and 30 mg of pseudoephedrine hydrochloride as the active ingredients [4] From Wikipedia. Were you taking the one that contains pseudoephedrine? Also, it is possible to have a paradoxical reaction to medications. For example, someone getting hyper after taking a benzodiazepine would be a paradoxical reaction. Or someone becoming more psychotic when they take an antipsychotic. Anyway, that doesn't really explain WHY you become hyper. It could be a bipolar thing or just something to do with your unique body. I personally think the pseudoephedrine reaction I have is a bipolar thing. Link to comment Share on other sites More sharing options...
deeschmee Posted May 16, 2013 Author Share Posted May 16, 2013 I'm pretty sure it was plain old Benadryl. I have never heard of the term paradoxical reaction but I'm glad I did,Do you know if bipolar people are more likely to have these reactions, or do other people get them as well?Very interesting, thank you! Link to comment Share on other sites More sharing options...
Luna- Posted May 16, 2013 Share Posted May 16, 2013 Just as an aside, my cat had a paradoxical reaction when I tried to sedate her for a longish car trip. It was an interesting journey! Link to comment Share on other sites More sharing options...
bookgirl Posted May 16, 2013 Share Posted May 16, 2013 A non-bipolar friend of mine has a paradoxical reaction to Benedryl and pseudoephedrine, combined or separately. There's really no way to tell if you'll have one until you take the meds. Link to comment Share on other sites More sharing options...
bluechick Posted May 16, 2013 Share Posted May 16, 2013 A paradox, by definition, is something that makes no logical sense. The phrase "paradoxical reaction", on its face, seems to mandate that they don't know why you react this way. My DH, for example, gets horribly sedated by non-drowsy cold or allergy meds. It's really weird and the doctors don't know why. I'm sorry that you're having such terrible sleeping. I hope the sleep study reveals something. Link to comment Share on other sites More sharing options...
deeschmee Posted May 16, 2013 Author Share Posted May 16, 2013 Just as an aside, my cat had a paradoxical reaction when I tried to sedate her for a longish car trip. It was an interesting journey!Oh NO! That couldn't have been fun! Link to comment Share on other sites More sharing options...
deeschmee Posted May 16, 2013 Author Share Posted May 16, 2013 bookgirl, I guess your right! I'm going to see if there is a common ingredient that maybe I react to. Further research is needed!Thank you bluechick, most everything about me is paradoxical!! Hahahaha! Seriously, I have some strange medical conditions as well. Mobile cecum, Chiari Malformation and an anterior herniated disc. Just they way it goes! I'll embrace the paradox! Link to comment Share on other sites More sharing options...
Recommended Posts