member Posted October 6, 2013 Share Posted October 6, 2013 Hi, In early spring my therapist and psychiatrist found out that I still have some depression even though I'm on 300mg of Lamictal and 25mg of Seroquel. They did testing and put me on Lexapro. It worked really well, after a couple of months my life got a lot better. But I had extreme sexual dysfunction. So my psychiatrist switched me to Wellbutrin but I had every adverse effect: puking, flu symptoms, zappy stuff, etc. AND it caused a little bit of mania or hypomania - probably something in-between. It was the old mania I used to have before I was on Lamictal, which was a lot of agitation/anger that I had no control over. There were some other heightened mania things that I only experience when a drug causes the mania or my brain runs low on Lamictal. So what the heck anti-depressant can I take that won't cause mania and won't cause me to gain weight? Am I doomed? This is making me sick, I'm so tired of being mentally ill. I just want to not be depressed, not gain weight, not have uncontrollable anger and continue to have sex with my husband. Before I got on Lamictal I tried: - prozac, didn't work - paxil, didn't work - effexor, didn't work - elavil, made me hate everybody and I wanted to hurt myself - celexa, caused hypomania and the next day I was re-diagnosed with bipolar disorder. I had been diagnosed a decade previously when I was a teenager but this time I was so sick of being out of control that I followed through with care. Now that I'm on a mood stabilizer I suppose it's time to go through all the SSRIs and SNRIs again. One drug that I haven't tried is Zoloft so that could be the final answer. But what. the. fuck!! I am so tired of trying to find the third drug that will eliminate my depression, I almost want to give up and deal with that lingering sadness on my own. My doctors will not be happy with that. Who's on a similar combo with similar problems? Anybody? I know a lot about these drugs but I don't know what one's gonna do it for my depression at this point. It's like playing poker and I'm sick of it. Thanks. Quote Link to comment Share on other sites More sharing options...
AnneMarie Posted October 6, 2013 Share Posted October 6, 2013 I take Lamictal and Latuda, a relatively new antipsychotic just approved for bipolar depression. It's an effective cocktail for me, and one without any real side effects. Talk to your pdoc. Quote Link to comment Share on other sites More sharing options...
mcjimjam Posted October 6, 2013 Share Posted October 6, 2013 I have found Cymbalta to be effective without the sexual SEs I had on SSRIs. I haven't gained weight either. Quote Link to comment Share on other sites More sharing options...
Jaytea Posted October 7, 2013 Share Posted October 7, 2013 I take Zoloft and Lamictal (among other things) and it has helped with my lows. Sexual SEs are frustrating. I've had problems with them, too. Especially when i was on Celexa. Quote Link to comment Share on other sites More sharing options...
MrTastybutt Posted October 7, 2013 Share Posted October 7, 2013 I never had a problem with Celexa and sex but I'm not bipolar. Seroquel left me frustrated in the bedroom. Quote Link to comment Share on other sites More sharing options...
member Posted October 7, 2013 Author Share Posted October 7, 2013 Thank you very much for the feedback. I'll ask about cymbalta and latuda next time I go in. Things are kind of dark now and I see how much I need an antidepressant. Quote Link to comment Share on other sites More sharing options...
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