Jump to content
CrazyBoards.org

Recommended Posts

I have dealt with OCD, anxiety and depression my whole life and tried many different antidepressants. A year ago I got off all the meds because I was experiencing extreme fatigue to the point that I was falling asleep at stoplights. They also didn't seem to be working well and I had tried many different meds prescribed by many different doctors over many different years. I have also tried therapy for the last ten years and tried different therapies.

 

Once I decided to get off the meds, I proceeded to see a ton of doctors all year long and had lots of expensive/extensive bloodwork done. They all had different ideas (most contradicting each other). I can send the 30 plus pages of bloodwork to anyone who wants to take a look. I had low t (total - not free, low vitamin c, low LDH and had aluminum as well as past epstein barr.

 

At this point I am not feeling too bad other than awful anxiety and depression. I saw a psychiatrist last month who recommended Pristiq and Deplin. I wanted to wait on the Pristiq but have started the Deplin. I didn't want to start down the med route again. I may have to, but I am scared to and don't want to end up in the fatigue boat as well as all of the side effects that made me get off of them in the first place. In researching the Deplin, someone had mentioned the a1298c. That sounded familiar so I looked at my bloodwork and googled. I am positive for 2 copies of the a1298c mutation. I am homozygous for the a1298c mutation and negative (normal) for the c677t mutation in the mthfr gene.

 

I just want to make sure that I am not doing anything detrimental and that I am doing the best that I can do. The Deplin is 15mg. I have been taking it for 2 weeks and don't feel anty different. Is this normal?

 

I am making healthy choices to try and fight this as well as therapy which never works for me. The only thing that I am taking is Vit D, Cod liver, spirulina and the Deplin 15mg. I am occasissonally taking ativan when needed.

 

Is it ok that I am taking that Deplin? Will it help me? Should I be taking or NOT taking anything else? Should I get periodic bloodwork to check my liver or anything else? Should I be conscious with anything else because of this mutation? Is there anything else that I should be doing/taking or not taking/avoiding? Is my anxiety related to this at all? Is it ok to take deplin? Can I drink moderately (couple of glasses of wine a week?)
 

My main concerns are that I am doing everything I can do and not doing anything that will cause me harm. I also need to take a break from all this testing/supplementing/focusing on my health. It has been a  draining year and I need a bit of a break (mentally and financially) I can't heal my gut, get off gluten, do chelation and such all at once. I have to break it down into small managable pieces.

 

One of the things that overwhelms me is that you don't need to take supplement x. When you do that you need to take these to balance that. You then need to do this and that and check this and that. I want to get off that boat for a while and focus on healthy eating/meditation/cardio/therapy.

 

I do have methylcobalamin injections that a doctor gave me. Should I be taking that? How much/how often? I am always confused by B vitamins in general. Can you take too much? Are they all water soluble and you just pee out any excess? Should I be taking Niacin?

 

Thank you in advance for any help that you can offer me. I apologize for the long message. Please let me know if you have any questions or need to know any of my levels.

 

Thanks

Link to comment
Share on other sites

I am on Deplin and it's helped me a lot with my fatigue. I noticed a difference within a day or two. My best guess (and no, I'm not a doctor or medical professional, so this is just my opinion) is that Deplin isn't going to help you on its own if it hasn't made a difference already. Deplin can enhance the effectiveness of antidepressants and other meds, though, so it may be that Deplin in combination with a drug such as Pristiq might be effective. That's how I take it, to make Prozac and Abilify more effective.

 

Best of luck to you in sorting out your situation. I know how hard and frustrating it can be; I went through several meds before stabilizing, and I'm still dealing with a lot of fatigue issues being caused by the Abilify. Please feel free to PM me if you want to talk more about Deplin or in general.

Link to comment
Share on other sites

Hi there.

 

You're asking some really complex questions all rolled into one post, so it's hard to break it down.

 

The short answer is to follow the recommendations of your care team. Find one pdoc and one tdoc that you like and that you can work with. If you want to talk about vitamin deficiencies, you might work with either your GP or pdoc to get answers on that. Some people find that naturopathic doctors (NDs) are appropriately trained and qualified to answer your questions as well.

 

The point is to find people you like and stick with them instead of seeing a bunch of different doctors. Each person is going to have a different theory about what's causing your symptoms and how to treat them. Find someone who uses approaches that are grounded in science that has been tested and replicated.

 

 

 

Is it ok that I am taking that Deplin? Will it help me? Should I be taking or NOT taking anything else? Should I get periodic bloodwork to check my liver or anything else? Should I be conscious with anything else because of this mutation? Is there anything else that I should be doing/taking or not taking/avoiding? Is my anxiety related to this at all? Is it ok to take deplin? Can I drink moderately (couple of glasses of wine a week?)

These questions really are best answered by your personal care team. Nobody here knows enough about you, nor is it appropriate for anyone on a peer internet support site to give you medical advice.

Link to comment
Share on other sites

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

 Share

×
×
  • Create New...