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Escitalopram (Cipralex/Lexapro)


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Hi all, I'm now 14 1/2 weeks in on the Cipralex, I've gone from under eating and under sleeping to over eating and over sleeping.  I've put on around 25 pounds since I started on it.  (I really don't need that much weight, although I started at normal weight (or slightly under), thankfully, but it can't continue.)  I'm still having suicidal thoughts and times when I really hate myself, I'm even having some times when I'm getting angry, I just feel very moody sometimes.  I went through a period before I was put on Risperidone that I was really hyper, and mildly hallucinating, but the pdoc says I definitely have MDD (and not bipolar).  I'm just wondering what these drugs are supposed to do?  I started on 10mg for 5 weeks and have been on 20mg for 9 weeks (the max recommended dose).

 

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I'm seeing my GP on Tuesday, she's the one who's been following me.  The Hospital said that she can contact them for a medication consult if she feels it necessary.  I'll be seeing a pdoc in a few months I suppose, I live in Canada where it's all about the public wait times.

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It sucks that you have to wait. Treatment resistant depression (or depression with suicidal thoughts) should always get a psychiatrist consult. Weight gain is really rare on lexapro (prescribing info says 1.8% compared to 1.5% on placebo). I tried googling the clinical trial info on rispiradone and couldn't find much, but anecdotal data suggests it may be more common. 

 

I'm glad you are seeing your GP again.

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I started gaining weight when I was only on the Cipralex, after it went up to 20mg from 10mg.  The Risperidone might not be helping but it started before-hand (I had put on at least 10 lbs before I started Risperidone).  I have disordered eating and actually contacted an eating disorder treatment facility last week.  I know part of my binge eating was self-harm related, and part of it is issues related to control.  

 

The biggest thing is that I'm still suicidally-depressed.

 

Oh and I think the grogginess was the Trazadone, but I had both Trazadone increased and Risperidone introduced at the same time.

Edited by Iowella
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I certainly agree that the depression still being so severe is a bigger concern than the weight gain. I know there are some other anti-psychotics which are generally considered to have better anti-depressant effects than Risperidone. Zyprexa and Abilify immediately come to mind, though you probably need a different anti-depressant at this point. You've been on the Lexapro long enough that it should be working, if it's going to work.

I hope you're able to get something more helpful soon.

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