chromegirl Posted May 15, 2014 Share Posted May 15, 2014 A week ago I finally got into a pdoc, who totally switched up my meds (for MDD and GAD). I had been on Lexapro 10 mg, and Straterra 40 mg, with 150 mg Trazodone to sleep. Then- BOOM- she switches me to Effexor XR 75 mg and Seroquel 50 mg, but lowered by Traz to 100 mg. Tonight I titrate the Seroquel up to 100 mg. Am I going to be a hungover basket case in the morning? I have had some great sleeps on the 50 mg, and only had the dreaded hangover the first morning...after that I was fine getting up in the mornings, really well rested actually. Just wondering if I am going to make my 9:00 a.m. appointment...yikes. Thanks all... Link to comment Share on other sites More sharing options...
Will Posted May 15, 2014 Share Posted May 15, 2014 I don't think they make the extended release in 100, so I guess that would be regular. I've forgotten. It might take a couple of days to get used to the increase. Maybe go to bed a little earlier to make your appt? But then try and get back to your regular schedule. I think it's important to keep on schedule. Link to comment Share on other sites More sharing options...
inabook Posted May 15, 2014 Share Posted May 15, 2014 I can't talk for anyone else, but it gave me a sort of hangover the first days + I slept 9-10 hours (I am now at 100mg, and no trouble waking up at all, but it took me a few days to adjust), so I'd go like Will, taking it early to make sure you have no problem in the morning. Link to comment Share on other sites More sharing options...
chromegirl Posted May 16, 2014 Author Share Posted May 16, 2014 Ok, thank you! It is 8:30 pm. here...going to take it now...fingers crossed Also, my pdoc said that the Seroquel is to combat the anxiety...I haven't noticed that effect at 50 mg...hopefully I will see some benefit at 100 mg. Thanks all. Link to comment Share on other sites More sharing options...
chromegirl Posted May 16, 2014 Author Share Posted May 16, 2014 I had a good night, I am happy to report...I took my 100 mg (yes it is the IR, not XR) at 8:45 pm.-ish, and I was zonked out in half an hour. So much so that I forgot to take the Trazodone I was supposed to take with it. I slept well, but actually woke up before my alarm, at 5:30...maybe because of not taking the traz? I have been taking trazodone for years and it really does improve my quality of sleep, i.e. no early waking. I guess the overall thing is that I didn't have the hangover, so that is good. Link to comment Share on other sites More sharing options...
Will Posted May 16, 2014 Share Posted May 16, 2014 Great! Yeah, IR hits you quicker. But I like that. XR does not work well for me when I'm ill. I like to be able to try and get to sleep soon after taking. Link to comment Share on other sites More sharing options...
inabook Posted May 16, 2014 Share Posted May 16, 2014 Glad to hear you had no problem waking up. IR takes 1 hour to hit for me, depending on whether/what I eat. Link to comment Share on other sites More sharing options...
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