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Hello, all.


I have a general question about antipsychotics, specifically regarding their use managing Bipolar 1 with psychotic features, schizoaffective disorder, and schizophrenia.


I have read that some antipsychotics have a stronger antipsychotic effect than others. Which meds are stronger for this, and which ones weaker?


I have responded very well to most antipsychotics I have taken, including Abilify twice when I was slowly transitioned from Risperdal to Abilify. However, once when I was switching from Seroquel XR back to Abilify, my doctor instructed that I stop the Seroquel XR and take the Abilify with no titration. I quickly went into a manic and psychotic episode. We kept raising the dose of Abilify, but to no avail. I ended up being hospitalized for ten days.


I am wondering if sometimes certain medications work better at maintaining a balanced state than they do at ending severe symptoms during an episode.


I have heard that Abilify can take longer than other antipsychotics to work, and I think having no cross-titration was a bad idea. I no longer have that doctor, and my current doctor does not want to make a judgment call on that.


Any insight would be appreciated.


Thank you!

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Abilify took about 7-8 weeks to work for me and it works really well.  My pdoc titrated up to my current dose.


But as to which works better/stronger, I think it depends on the person.

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