sheismistaken Posted December 3, 2005 Share Posted December 3, 2005 I am seeing my pdoc on Thursday and I am feeling a med change coming on. I asked him last month about switching to an SSRI to help combat my compulsive thoughts (SI and shoplifting). He said he'd rather increase my Seroquel (which he did from 50 mg qhs to 100 mg qhs), and increase my Effexor from 150 mg to 225. I told him that this summer my doc had increased my Effexor to 225 and I went a little crazy and ended up in the hospital for 5 days. Immediately the pdoc there decreased my Effexor and the craziness went away after a couple days. My pdoc now says that he'd have me take 150 mg in the morning and 75 in the afternoon. I know it does make a difference in how you take something but if I had that kind of reaction the first time...isn't it likely that it will happen again? I think it was a mixed episode...my tdoc says a hypomanic episode. Either way it means bipolar and wouldn't you think he'd stay away from increasing it again? Link to comment Share on other sites More sharing options...
HaloGirl66 Posted December 3, 2005 Share Posted December 3, 2005 personally, if you had a bad experiance with a drug before and you are not comfortable taking something then follow you gut and tell your doc that you would like to try something else. increasing your effexor can't be the only choice you have. Link to comment Share on other sites More sharing options...
Velvet Elvis Posted December 4, 2005 Share Posted December 4, 2005 If it's the sustained release stuff it shouldn't make a whole lot of difference but if it's short acting it could make a big difference. The seroquel could help prevent the reaction you had before. FWIW, OCD generally responds to SSRIs at much higher doses than are required for depression, so if you are bipolar it's possible you won't be able to tolerate any of them at the doses required. 225 mgs and up is where 'fex is thought to have an effect on norepenephrine. It's possible that you are particularly sensitive to it and are experiencing something like another round of startup side effects. Some stimulation would be normal here. Again, it's possible that seroquel could reduce this. Also, if you're feeling real shitty to begin with, effexor discontinuation is one of the last things you want to deal with right now. Link to comment Share on other sites More sharing options...
Min Posted December 4, 2005 Share Posted December 4, 2005 If it's the sustained release stuff it shouldn't make a whole lot of difference but if it's short acting it could make a big difference. The seroquel could help prevent the reaction you had before. FWIW, OCD generally responds to SSRIs at much higher doses than are required for depression, so if you are bipolar it's possible you won't be able to tolerate any of them at the doses required. 225 mgs and up is where 'fex is thought to have an effect on norepenephrine. It's possible that you are particularly sensitive to it and are experiencing something like another round of startup side effects. Some stimulation would be normal here. Again, it's possible that seroquel could reduce this. Also, if you're feeling real shitty to begin with, effexor discontinuation is one of the last things you want to deal with right now. <{POST_SNAPBACK}> agreed. i would just stay at the dose you are on. effexor had some nasty side effects when i upped it (severe mood swings, nightmares) and seroquel seemed to balance that out. talk to your doctor. but i wouldn't recommend going of effexor, i'm even afraid to. Link to comment Share on other sites More sharing options...
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